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Liposome Phase Systems as Membrane Activity Sensors for Peptides

  • Chapter
Lipid Bilayers

Part of the book series: Biological Physics Series ((BIOMEDICAL))

Abstract

Anyone who is able to shake a beaker can make liposomes. The ease of liposome preparation is one of the secrets behind their success in many fields of science and technology. They are, however, among the most ill-defined and tricky systems as far as their physical chemistry is concerned. Here are just a few of their shortcomings:

  • size and shape heterogeneity, encompassing vastly different numbers of bilayer shells.

  • internal heterogeneity with regard to local solvation and curvature.

  • stacking defects.

  • not in thermodynamic equilibrium.

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  1. Peter Laggner
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Laggner, P., Lohner, K. (2001). Liposome Phase Systems as Membrane Activity Sensors for Peptides. In: Lipid Bilayers. Biological Physics Series. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04496-4_11

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  • DOI: https://doi.org/10.1007/978-3-662-04496-4_11

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