Abstract
Since the introduction of carbazepine (Tegretol®, CBZ) in 1963 it has been widely used for the treatment of certain types of epilepsy, trigeminal neuralgia, etc. Subsequently, numerous reports on its clinical efficacy were issued. In 1964, the first study on the tolerance of carbamazepine was published (Krüger, 1964).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Beyer, K.-H., Klinge, D.: Zum spektrophotometrisdien Nachweis von Carbamazepin. Arzneimittel-Forsch. (Drug Res.) 19, 1759 (1969).
Cereghino, J. , van Meter, J. C., Brock, J. T., Penry, J. K., Smith, L. D., White, B. G.: Preliminary observations of serum carbamazepine concentration in epileptic patients. Neurology (Minneap.) 23, 357 (1973).
Christiansen, J.: Assay of carbamazepine and metabolites in plasma by quantitative thin-layer chromatography. In: Methods of Analysis of Anti-Epileptic Drugs (eds. J. W. A. Meijer, H. Meinardi, C. Gardner-Thorpe, E. van der Kleijn), pp. 87–89. Amsterdam: Excerpta Medica, New York: American Elsevier Co., Inc. (1973).
Frey, H., Yrjänä, T.: Carbamazepine titers of epileptic patients. Scand. J. clin. Lab. Invest. 25, Suppl. 113, 90 (1970).
Führ, J.: Untersuchungen über die Verträglichkeit und Ausscheidung eines neuartigen Antiepilepticums. Arzneimittel-Forsch. (Drug Res.) 14, 74 (1964).
Herrmann, B.: Personal communication (1964).
Krüger, H.-J.: Klinischer Beitrag zur Therapie der Epilepsie mit einem Azepinderivat. Med. Welt 26/64, 1407 (1964).
Kupferberg, H. J.: GLC determination of carbamazepine in plasma. J. pharm. Sci. 61, 284 (1972).
Larsen, N.-E., Wendelboe, J., Bohn, L.: Determination of carbamazepine (Tegretol®) by gas chromatography. Scand. J. clin. Lab. Invest. Suppl. 110, 35 (1969).
Meijer, J. W. A.: Simultaneous quantitative determination of antiepileptic drugs, including carbamazepine, in body fluids. Epilepsia 12, 341 (1971).
Meinardi, H.: Carbamazepine. In: Antiepileptic Drugs (eds. D. M. Woodbury, J. K. Penry, R. P. Schmidt), pp. 487–496. New York: Raven Press 1973.
Moller, J.: Determination of serum concentration of carbamazepine in child neurology. In: Plasmakoncentrations-Bestämningar Av Antiepileptika: Metodologiska Och Kliniska Aspekter, Konferens Lidingö 1971, Referat av Lars Lund, pp. 72–79 (1971).
Nielsen, H. R., Remmer, H.: Kvantitativ bestemmelse av karbamazepin (Tegretol®) i serum. Ugeskr. Laeg. 131, 2200 (1969).
Parsonage, M.: Clinical experience with carbamazepine (Tegretol®) as an anticonvulsant. In: Tegretol in Epilepsy (ed. C. A. S. Wink), pp. 69–79. Manchester: C. Nicholls and Company Ltd. 1972.
Scheiffarth, F., Weist, F., Zicha, L.: Zum Nachweis von 5-Carbamayl-5H-dibenzo(b,f)azepin im Liquor cerebrospinalis mittels Dünnschichtchromatographie. Z. klin. Chem. 4, 68 (1966).
Schneider, H.: Carbamazepine: The influence of other anti-epileptic drugs on its serum level. In: Clinical Pharmacology of Anti-Epileptic Drugs (Eds. H. Schneider, D. Janz, C. Gardner-Thorpe, H. Meinardi, A. L. Sherwin), p. 189. Berlin-Heidelberg-New York: Springer 1975.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1975 Springer-Verlag Berlin-Heidelberg
About this paper
Cite this paper
Schneider, H. (1975). Carbamazepine: An Attempt to Correlate Serum Levels with Anti-Epileptic and Side Effects. In: Schneider, H., Janz, D., Gardner-Thorpe, C., Meinardi, H., Sherwin, A.L. (eds) Clinical Pharmacology of Anti-Epileptic Drugs. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85921-2_14
Download citation
DOI: https://doi.org/10.1007/978-3-642-85921-2_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-85923-6
Online ISBN: 978-3-642-85921-2
eBook Packages: Springer Book Archive