Abstract
A granuloma may be defined as a collection of cells of the monocyte-macrophage system with or without the additional presence of other inflammatory cells [14]. Granulomas may be classified according to whether they are of immunological or non-immunological origin.
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Immunological e.g. tuberculosis, tuberculoid leprosy, syphilis, schistosomiasis, sarcoidosis, berillium, zirconium.
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Non-immunological, a) non-toxic, e.g. plastic beads, carbon particles, non-toxic metals (Fe); b) toxic, e.g. silica, talc, asbestos; c) activation of C3, e.g. carageenan, kaolin, aluminium hydroxide, lepromatous leprosy.
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References
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© 1981 Springer-Verlag Berlin Heidelberg New York
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Turk, J.L., Narayanan, R.B. (1981). The Monocyte-Macrophage System In Granulomatous Inflammation. In: Schmalzl, F., Huhn, D., Schaefer, H.E. (eds) Disorders of the Monocyte Macrophage System. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81696-3_11
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DOI: https://doi.org/10.1007/978-3-642-81696-3_11
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