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Revascularization of Free Autologous Nerve Grafts

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Peripheral Nerve Lesions

Abstract

It is known today that regeneration in nerve grafts requires “isomorphic” conditions, i.e., a preserved endoneural architecture and the survival of the Schwann’s cells within the graft. Only the preserved vitality of Schwann’s cells offers the essential precondition for the breakdown of the myelin and subsequent final removal of degenerated axons by macrophages [1]. Furthermore, the Schwann’s cells form a new and, as is well-known, indispensable myelin sheath along the newly formed axon sprouting.

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References

  1. Asbury AK (1975) The biology of Schwann cells. In: Dyck PJ, Thomas PK, Lambert EH (eds) Peripheral neuropathy. Saunders, Philadelphia London Toronto, pp 201–212.

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  2. Hiller F (1949) Die Bedeutung des mesodermalen Gewebes bei der Nervenregeneration. Experimentelle Untersuchungen an Nervenverletzungen und Transplantaten. Dtsch Z Nervenheilk 160:176–195.

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  4. Weiss P, Taylor C (1946) The viability of isolated nerve fragments and its modification by methylene blue. J Cell Comp Physiol 27:87–103.

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© 1990 Springer-Verlag Berlin Heidelberg

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Penkert, G., Samii, M. (1990). Revascularization of Free Autologous Nerve Grafts. In: Samii, M. (eds) Peripheral Nerve Lesions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75611-5_21

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  • DOI: https://doi.org/10.1007/978-3-642-75611-5_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75613-9

  • Online ISBN: 978-3-642-75611-5

  • eBook Packages: Springer Book Archive

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