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Prevention of Vasospasm with Nimodipine

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Stabilizing Craniocervical Operations Calcium Antagonists in SAH Current Legal Issues

Part of the book series: Advances in Neurosurgery ((NEURO,volume 18))

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Abstract

Vasospasm is a secondary complication of subarachnoid hemorrhage (SAH), occurring 4–14 days after the bleeding [18,42]. Angiographic investigations have revealed the incidence of “angiographic vasospasm” to be 30%–70% [3,14,17,25,35, 36,42]. This correlates well with the blood flow velocity changes in the basal arteries detected by transcranial Doppler sonography (TCD). A velocity increase of more than twice the baseline value as a sign of a marked vessel diameter reduction is found in TCD in about 70% of patients [1,18–20,37]. Angiographic vasospasm and “Doppler sonographic vasospasm” do not correlate with the clinical symptoms. Only 15%–30% [11,12,21,22] of patients with vasospasm after aneurysmal SAH develop a “clinical or symptomatic vasospasm” with transient or permanent delayed ischemic deficits (DIDs).

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Authors and Affiliations

  1. Neurochirurgische Universitätsklinik, Hugstetter Str. 55, D-7800, Freiburg i.Br., Germany

    A. Härders

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  1. J. Gilsbach
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  2. A. Härders
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Editors and Affiliations

  1. Neurochirurgische Universitätsklinik, Josef-Schneider-Straße 11, D-8700, Würzburg, Germany

    K.-A. Bushe

  2. Neurochirurgische Klinik und Poliklinik, Universitätsklinikum Steglitz, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Germany

    Mario Brock

  3. Neurochirurgische Klinik, Universität Erlangen-Nürnberg, Schwabachanlage 6 (Kopfklinikum), D-8520, Erlangen, Germany

    Margareta Klinger

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© 1990 Springer-Verlag Berlin Heidelberg

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Gilsbach, J., Härders, A. (1990). Prevention of Vasospasm with Nimodipine. In: Bushe, KA., Brock, M., Klinger, M. (eds) Stabilizing Craniocervical Operations Calcium Antagonists in SAH Current Legal Issues. Advances in Neurosurgery, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75283-4_43

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  • DOI: https://doi.org/10.1007/978-3-642-75283-4_43

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51967-6

  • Online ISBN: 978-3-642-75283-4

  • eBook Packages: Springer Book Archive

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