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Chitin: Structure, Metabolism, and Regulation of Biosynthesis

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Book cover Plant Carbohydrates II

Part of the book series: Encyclopedia of Plant Physiology ((921,volume 13 / B))

Abstract

Chitin is ans ubiquitous component of fungal cell walls. Only a few classes of fungi, such as the Oomycetes and Trichomycetes (Bartnicki-Garcia 1968) appear to lack chitin. Even in species of the Saccharomycetaceae, which were classified as devoid of chitin by Bartnicki-Garcia, small amounts of the polysaccharide are found in the cell wall, with a preferential localization in the septum (Cabib et al. 1974). Because of its function in the generation and maintenance of cell shape and in the formation of septa, chitin is of great importance in fungal growth and physiology. For the same reasons, it constitutes a very useful model for the study of morphogenetic processes. Hence the interest of many investigators in this polysaccharide, which may be considered the equivalent, for fungi, of cellulose in the plant kingdom.

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References

  • Archer DB (1977) Chitin biosynthesis in protoplasts and subcellular fractions of Aspergillus fumigatus. Biochem J 164: 653–658

    PubMed  CAS  Google Scholar 

  • Arroyo-Begovich A, Herrera JR (1979) Proteolytic activation and inactivation of chitin synthase from Neurospora crassa. J Gen Microbiol 113: 339–345

    CAS  Google Scholar 

  • Ballou CE, Maitra SK, Walker JW, Whelan WL (1977) Developmental defects associated with glucosamine auxotrophy in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 74: 4351–4355

    PubMed  CAS  Google Scholar 

  • Bartnicki-Garcia S (1968) Cell wall chemistry, morphogenesis and taxonomy of fungi. Annu Rev Microbiol 22: 87–108

    PubMed  CAS  Google Scholar 

  • Bartnicki-Garcia S, Lippman E (1969) Cell wall construction in Mucor rouxii. Science 165: 302–304

    PubMed  CAS  Google Scholar 

  • Bartnicki-Garcia S, Lippman E (1972) Inhibition of Mucor rouxii by polyoxin D: effects on chitin synthetase and morphological development. J Gen Microbiol 71: 301–309

    CAS  Google Scholar 

  • Bartnicki-Garcia S, Lippman E (1977) Polarization of cell wall synthesis during spore-germination of Mucor rouxii. Exp Mycol 1: 230–240

    Google Scholar 

  • Bartnicki-Garcia S, Bracker CE, Reyes E, Ruiz-Herrera J (1978) Isolation of chitosomes from taxonomically diverse fungi and synthesis of chitin microfibrils in vitro. Exp Mycol 2: 173–192

    CAS  Google Scholar 

  • Bauer H, Horisberger M, Bush DA, Sigarlakie E (1972) Mannan as a major component of the bud scars of Saccharomyces cerevisiae. Arch Mikrobiol 85: 202–208

    PubMed  CAS  Google Scholar 

  • Benitez T, Villa TG, Garcia Acha I (1976) Effect of polyoxin D on germination, morphological development and biosynthesis of the cell wall of Trichoderma viride. Arch Microbiol 108: 183–188

    PubMed  CAS  Google Scholar 

  • Beran K, Holan Z, Baldrian J (1972) The chitin-glucan complex in Saccharomyces cerevisiae I. IR and X-ray observations. Folia Microbiol 17: 322–330

    CAS  Google Scholar 

  • Betz H, Hinze H, Holzer H (1974) Isolation and properties of two inhibitors of proteinase B from yeast. J Biol Chem 249: 4515–4521

    PubMed  CAS  Google Scholar 

  • Bowers B, Levin G, Cabib E (1974) Effect of polyoxin D on chitin synthesis and septum formation in Saccharomyces cerevisiae. J Bacteriol 119:564–575

    PubMed  CAS  Google Scholar 

  • Bracker CE, Ruiz-Herrera J, Bartnicki-Garcia S (1976) Structure and transformation of chitin synthetase particles (chitosomes) during microfibril synthesis in vitro. Proc Natl Acad Sci USA 73: 4570–4574

    PubMed  CAS  Google Scholar 

  • Braun PC, Calderone RA (1978) Chitin synthesis in Candida albicans: comparison of yeast and hyphal forms. J Bacteriol 133: 1472–1477

    PubMed  CAS  Google Scholar 

  • Braun PC, Calderone RA (1979) Regulation and solubilization of Candida albicans chitin synthetase. J Bacteriol 140: 666–670

    PubMed  CAS  Google Scholar 

  • Cabib E, Bowers B (1971) Chitin and yeast budding. Localization of chitin in yeast bud scars. J Biol Chem 246: 152–159

    PubMed  CAS  Google Scholar 

  • Cabib E, Bowers B (1975) Timing and function of chitin synthesis in yeast. J Bacteriol 124: 1586–1593

    PubMed  CAS  Google Scholar 

  • Cabib E, Farkas V (1971) The control of morphogenesis: an enzymatic mechanism for the initiation of septum formation in yeast. Proc Natl Acad Sci USA 68: 2052–2056

    PubMed  CAS  Google Scholar 

  • Cabib E, Keller FA (1971) Chitin and yeast budding. Allosteric inhibition of chitin synthetase by a heat-stable protein from yeast. J Biol Chem 246: 167–173

    PubMed  CAS  Google Scholar 

  • Cabib E, Ulane R (1973) Chitin synthetase activating factor from yeast, a protease. Biochem Biophys Res Commun 50: 186–191

    PubMed  CAS  Google Scholar 

  • Cabib E, Ulane R, Bowers B (1973) Yeast chitin synthetase. Separation of the zymogen from its activating factor and recovery of the latter in the vacuole fraction. J Biol Chem 248: 1451–1458

    PubMed  CAS  Google Scholar 

  • Cabib E, Ulane R, Bowers B (1974) A molecular model for morphogenesis: the primary septum of yeast. In : Horecker BL, Stadtman ER (eds) Current topics in cellular regulation, vol VIII. Academic Press, London New York, pp 1–32

    Google Scholar 

  • Cabib E, Duran A, Bowers B (1979) Localized activation of chitin synthetase in the initiation of yeast septum formation. In: Burnett JH, Trinci APJ (eds) Fungal walls and hyphal growth. Cambridge Univ Press, Cambridge, pp 189–201

    Google Scholar 

  • Campbell JMcA, Peberdy JF (1979) Proteases of Aspergillus nidulans and the possible role of a neutral component in the activation of chitin synthase zymogen. FEMS Microbiol Lett 6: 65–69

    CAS  Google Scholar 

  • Cantino EC, Myers RB (1972) Concurrent effect of visible light on γ-particles, chitin synthetase, and encystment capacity in zoospores in Blastocladiella emersonii. Arch Mikrobiol 83: 203–215

    PubMed  CAS  Google Scholar 

  • Cantino EC, Myers RB (1974) Basic mechanisms in plant morphogenesis. Brookhaven Symp Biol 25: 51–74

    CAS  Google Scholar 

  • Carlström D (1957) The crystal structure of α-chitin. J Biophys Biochem Cytol 3: 669–683

    PubMed  Google Scholar 

  • Craig GD, Newsam RJ, Gull K, Wood DA (1979) An ultrastructural and autoradiographic study of stipe elongation in Agaricus bisporus. Protoplasma 98: 15–29

    Google Scholar 

  • Darken MA (1961) Application of fluorescent brighteners in biological techniques. Science 133: 1704–1705

    PubMed  CAS  Google Scholar 

  • Davidson EA (1966) Metabolism of amino sugars. In: Balazs EA, Jeanloz RW (eds) The amino sugars, vol IIB. Academic Press, London New York, pp 1–14

    Google Scholar 

  • Davidson EA, Blumenthal HJ, Roseman S (1957) Glucosamine metabolism II Studies on glucosamine 6-phosphate N-acetylase. J Biol Chem 226: 125–133

    PubMed  CAS  Google Scholar 

  • Durán A, Cabib E (1978) Solubilization and partial purification of yeast chitin synthetase. Confirmation of the zymogenic nature of the enzyme. J Biol Chem 253: 4419–4425

    PubMed  Google Scholar 

  • Durán A, Bowers B, Cabib E (1975) Chitin synthetase zymogen is attached to the yeast plasma membrane. Proc Natl Acad Sci USA 72: 3952–3955

    PubMed  Google Scholar 

  • Durán A, Cabib E, Bowers B (1979) Chitin synthetase distribution on the yeast plasma membrane. Science 203: 363–365

    PubMed  Google Scholar 

  • Endo A, Kakiki K, Misato T (1970) Mechanism of action of the antifungal agent polyoxin D. J Bacteriol 104: 189–196

    PubMed  CAS  Google Scholar 

  • Farkas V (1979) Biosynthesis of cell walls of fungi. Microbiol Rev 43: 117–144

    PubMed  CAS  Google Scholar 

  • Galun E (1972) Morphogenesis of Trichoderma: autoradiography of intact colonies labeled by [3H]N-acetylglucosamine as a marker of new cell wall biosynthesis. Arch Mikrobiol 86: 305–314

    PubMed  CAS  Google Scholar 

  • Galun M, Braun A, Frensdorff A, Galun E (1976) Hyphal walls of isolated lichen fungi. Autoradiographic localization of precursor incorporation and binding of fluorescein-conjugated lectins. Arch Microbiol 108: 9–16

    PubMed  CAS  Google Scholar 

  • Ghosh S, Blumenthal HJ, Davidson E, Roseman S (1960) Glucosamine metabolism V. Enzymatic synthesis of glucosamine 6-phosphate. J Biol Chem 235: 1265–1273

    PubMed  CAS  Google Scholar 

  • Glaser L, Brown DH (1957) The synthesis of chitin in cell-free extracts of Neurospora crassa. J Biol Chem 228: 729–742

    PubMed  CAS  Google Scholar 

  • Gooday GW (1971) An autoradiographic study of hyphal growth of some fungi. J Gen Microbiol 67: 125–133

    CAS  Google Scholar 

  • Gooday GW (1972) The effect of polyoxin D on morphogenesis in Coprinus cinereus. Biochem J 129: 17P

    Google Scholar 

  • Gooday GW (1979) Chitin synthesis and differentiation in Coprinus cinereus. In: Burnett JH, Trinci APJ (eds) Fungal walls and hyphal growth. Cambridge Univ Press, Cambridge, pp 203–223

    Google Scholar 

  • Gooday GW, Rousset-Hall A (1975) Properties of chitin synthetase from Coprinus cinereus. J Gen Microbiol 89: 137–145

    Google Scholar 

  • Gooday GW, Rousset-Hall A, Hunsley D (1976) Effect of polyoxin D on chitin synthesis in Coprinus cinereus. Trans Br Mycol Soc 67: 193–200

    Google Scholar 

  • Hackman RH, Goldberg M (1974) Light-scattering and infrared-spectrophotometric studies of chitin and chitin derivatives. Carbohydr Res 38: 35–45

    CAS  Google Scholar 

  • Hasilik A (1974) Inactivation of chitin synthase in Saccharomyces cerevisiae. Arch Microbiol 101: 295–301

    PubMed  CAS  Google Scholar 

  • Hasilik A, Muller H, Holzer H (1974) Compartmentation of the tryptophan-synthase- proteolyzing system in Saccharomyces cerevisiae. Eur J Biochem 48: 111–117

    CAS  Google Scholar 

  • Hata T, Hayashi R, Doi E (1967) Purification of yeast proteinases. I. Fractionation and some properties of the proteinases. Agric Biol Chem 31: 150–159

    CAS  Google Scholar 

  • Hayashibe M, Katohda S (1973) Initiation of budding and chitin ring. J Gen Appl Microbiol 19: 23–39

    CAS  Google Scholar 

  • Hori M, Kakiki K, Suzuki S, Misato T (1971) Studies on the mode of action of polyoxins. Part III. Relation of polyoxin structure to chitin synthetase inhibition. Agric Biol Chem 35: 1280–1291

    CAS  Google Scholar 

  • Hori M, Eguchi J, Kakiki K, Misato T (1974a) Studies on the mode of action of polyoxins. VI. Effect of polyoxin B on chitin synthesis in polyoxin-sensitive and resistant strains of Alternaria kikuchiana. J Antibiot 27: 260–266

    PubMed  CAS  Google Scholar 

  • Hori M, Kakiki K, Misato T (1974b) Further study on the relation of polyoxin structure to chitin synthetase inhibition. Agric Biol Chem 38: 691–698

    CAS  Google Scholar 

  • Hori M, Kakiki K, Misato T (1974c) Interaction between polyoxin and active center of chitin synthetase. Agric Biol Chem 38: 699–705

    CAS  Google Scholar 

  • Horisberger M, Vonlanthen M (1977) Location of mannan and chitin on thin sections of budding yeasts with gold markers. Arch Microbiol 115: 1–7

    PubMed  CAS  Google Scholar 

  • Huang KP, Cabib E (1974) Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. II. The effect of proteolysis. J Biol Chem 249: 3858–3861

    PubMed  CAS  Google Scholar 

  • Hunsley D, Burnett JH (1970) The ultrastructural architecture of the walls of some hyphal fungi. J Gen Microbiol 62: 203–218

    CAS  Google Scholar 

  • Isaac S, Ryder NS, Peberdy JF (1978) Distribution and activation of chitin synthase in protoplast fractions released during the lytic digestion of Aspergillus nidulans hyphae. J Gen Microbiol 105: 45–50

    CAS  Google Scholar 

  • Isono K, Asahi K, Suzuki S (1969) Studies on polyoxins, antifungal antibiotics. XIII The structure of polyoxins. J Am Chem Soc 91: 7490–7505

    PubMed  CAS  Google Scholar 

  • Jan YN (1974) Properties and cellular localization of chitin synthetase in Phycomyces blakesleeanus J Biol Chem 249: 1973–1979

    CAS  Google Scholar 

  • Jaworski EG, Wang LC, Carpenter WD (1965) Biosynthesis of chitin in cell-free extracts of Venturia inaequalis. Phytopathology 55: 1309–1312

    CAS  Google Scholar 

  • Katz D, Rosenberger RF (1970) A mutation in Aspergillus nidulans producing hyphal walls which lack chitin. Biochim Biophys Acta 208: 452–460

    PubMed  CAS  Google Scholar 

  • Katz D, Rosenberger RF (1971 a) Lysis of an Aspergillus nidulans mutant blocked in chitin synthesis and its relation to wall assembly and wall metabolism. Arch Mikrobiol 80: 284–292

    PubMed  CAS  Google Scholar 

  • Katz D, Rosenberger RF (1971 b) Hyphal wall synthesis in Aspergillus nidulans: effect of protein synthesis inhibition and osmotic shock on chitin insertion and morphogenesis. J Bacteriol 108: 184–190

    PubMed  CAS  Google Scholar 

  • Keller FA, Cabib E (1971) Chitin and yeast budding. Properties of chitin synthetase from Saccharomyces cerevisiae. J Biol Chem 246: 160–166

    PubMed  CAS  Google Scholar 

  • Kornfeld R (1967) Studies on l-glutamine d-fructose 6-phosphate amidotransferase. J Biol Chem 242: 3135–3141

    PubMed  CAS  Google Scholar 

  • Kornfeld S, Kornfeld R, Neufeld EF, O’Brien PJ (1964) The feedback control of sugar nucleotide biosynthesis in liver. Proc Natl Acad Sci USA 52: 371–379

    PubMed  CAS  Google Scholar 

  • Lehle L, Tanner W (1976) The specific site of tunicamycin inhibition in the formation of dolichol-bound N-acetylglucosamine derivatives. FEBS Lett 71: 167–170

    CAS  Google Scholar 

  • Leloir LF, Cardini CE (1953) The biosynthesis of glucosamine. Biochim Biophys Acta 12: 15–22

    PubMed  CAS  Google Scholar 

  • Lenney JF, Dalbec JM (1967) Purification and properties of two proteinases from Saccharomyces cerevisiae. Arch Biochem Biophys 120: 42–48

    PubMed  CAS  Google Scholar 

  • Lenney JF, Dalbec JM (1969) Yeast proteinase B: identification of the inactive form as an enzyme-inhibitor complex. Arch Biochem Biophys 129: 407–409

    PubMed  CAS  Google Scholar 

  • Lenney JF, Matile P, Wiemken A, Schellenberg M, Meyer J (1974) Activities and cellular localization of yeast proteases and their inhibitors. Biochem Biophys Res Commun 60: 1378–1383

    PubMed  CAS  Google Scholar 

  • López-Romero E, Ruiz-Herrera J (1976) Synthesis of chitin by particulate preparations from Aspergillus flavus. Antonie van Leeuwenhoek J Microbiol Serol 42: 261–276

    Google Scholar 

  • López-Romero E, Ruiz-Herrera J, Bartnicki-Garcia S (1978) Purification and properties of an inhibitor protein of chitin synthetase from Mucor rouxii. Biochim Biophys Acta 525: 338–345

    PubMed  Google Scholar 

  • Lovett JS (1975) Growth and differentiation of the water mold Blastocladiella emersonii: cytodifferentiation and the role of ribonucleic acid and protein synthesis. Bacteriol Rev 39: 345–404

    PubMed  CAS  Google Scholar 

  • Maier K, Müller H, Tesch R, Trolp R, Witt I, Holzer H (1979) Primary structure of yeast proteinase B inhibitor 2. J Biol Chem 254: 12555–12561

    PubMed  CAS  Google Scholar 

  • Marchant R, Smith DG (1968) Bud formation in Saccharomyces cerevisiae and a comparison with the mechanism of cell division in other yeasts. J Gen Microbiol 53: 163–169

    PubMed  CAS  Google Scholar 

  • McMurrough I, Bartnicki-Garcia S (1971) Properties of a particulate chitin synthetase from Mucor rouxii. J Biol Chem 246: 4008–4016

    PubMed  CAS  Google Scholar 

  • McMurrough I, Bartnicki-Garcia S (1973) Inhibition and activation of chitin synthesis by Mucor rouxii cell extracts. Arch Biochem Biophys 158: 812–816

    PubMed  CAS  Google Scholar 

  • McMurrough I, Flores-Carreon A, Bartnicki-Garcia S (1971) Pathway of chitin synthesis and cellular localization of chitin synthetase in Mucor rouxii. J Biol Chem 246: 3999–4007

    PubMed  CAS  Google Scholar 

  • Mills GL, Cantino EC (1978) The lipid composition of the Blastocladiella emersonii y-particle and the function of γ-particle lipid in chitin formation. Exp Mycol 2: 99–109

    CAS  Google Scholar 

  • Minke R, Blackwell J (1978) The structure of α-chitin. J Mol Biol 120: 167–181

    PubMed  CAS  Google Scholar 

  • Mitani M, Inoue Y (1968) Antagonists of antifungal substance polyoxin. J Antibiot 21: 492–496

    PubMed  CAS  Google Scholar 

  • Molano J, Polachek I, Duran A, Cabib E (1979) An endochitinase from wheat germ. Activity on nascent and preformed chitin. J Biol Chem 254: 4901–4907

    PubMed  CAS  Google Scholar 

  • Molano J, Bowers B, Cabib E (1980) Distribution of chitin in the yeast cell wall. An ultrastructural and chemical study. J Cell Biol 85: 199–212

    PubMed  CAS  Google Scholar 

  • Moore PM, Peberdy JF (1975) Biosynthesis of chitin by particulate fractions from Cunning-hamella elegans. Microbios 12: 29–39

    PubMed  CAS  Google Scholar 

  • Moore PM, Peberdy JF (1976) A particulate chitin synthase from Aspergillus flavus Link: the properties, location and levels of activity in mycelium and regenerating protoplast preparation. Can J Microbiol 22: 915–921

    PubMed  CAS  Google Scholar 

  • Moriguchi M, Yamamoto K, Kawai H, Tochikura T (1976) The partial purification of l-glutamine d-fructose 6-phosphate amidotransferase from baker’s yeast. Agric Biol Chem 40: 1655–1656

    CAS  Google Scholar 

  • Muzzarelli RA (1977) Chitin. Pergamon Press, Oxford

    Google Scholar 

  • Norman J, Giddings TH, Cantino EC (1975) Partial purification and properties of l-glutamine: D-fructose 6-phosphate amidotransferase from zoospores of Blastocladiella emersonii. Phytochemistry 14: 1271–1274

    Google Scholar 

  • Ohta N, Kakiki K, Misato T (1970) Studies on the mode of action of polyoxin D. II Effect of polyoxin D on the synthesis of fungal cell wall chitin. Agric Biol Chem 34: 1224–1234

    CAS  Google Scholar 

  • Parodi AJ, Leloir LF (1979) The role of lipid intermediates in the glycosylation of proteins in the eucaryotic cell. Biochim Biophys Acta 559: 1–37

    PubMed  CAS  Google Scholar 

  • Peberdy JF, Moore PM (1975) Chitin synthase in Mortierella vinacea: properties, cellular location and synthesis in growing cultures. J Gen Microbiol 90: 228–236

    PubMed  CAS  Google Scholar 

  • Plessmann Camargo E, Dietrich CP, Sonneborn D, Strominger JL (1967) Chitin synthesis in spores and vegetative cells of Blastocladiella emersonii. J Biol Chem 242: 3121–3128

    Google Scholar 

  • Polacheck I, Rosenberger RF (1978) Distribution of autolysins in hyphae of Aspergillus nidulans: evidence for a lipid mediated attachment to hyphal walls. J Bacteriol 135: 741–747

    PubMed  CAS  Google Scholar 

  • Porter CA, Jaworski EG (1966) The synthesis of chitin by particulate preparations of Allomyces macrogynus. Biochemistry 5: 1149–1154

    PubMed  CAS  Google Scholar 

  • Reissig JL (1956) Phosphoacetylglucosamine mutase of Neurospora. J Biol Chem 219: 753–767

    PubMed  CAS  Google Scholar 

  • Rosenberger RF (1976) The cell wall. In: Smith JE, Berry DR (eds) The filamentous fungi, vol II. Edward Arnold, London, pp 328–344

    Google Scholar 

  • Rousset-Hall A, Gooday GW (1975) A kinetic study of a solubilized chitin synthetase preparation from Coprinus cinereus. J Gen Microbiol 89: 146–154

    Google Scholar 

  • Ruiz-Herrera J, Bartnicki-Garcia S (1976) Proteolytic activation and inactivation of chitin synthetase from Mucor rouxii. J Gen Microbiol 97: 241–249

    PubMed  CAS  Google Scholar 

  • Ruiz-Herrera J, Sing VO, Van der Woude WJ, Bartnicki-Garcia S (1975) Microfibril assembly by granules of chitin synthetase. Proc Natl Acad Sci USA 72: 2706–2710

    PubMed  CAS  Google Scholar 

  • Ruiz-Herrera J, Lopez-Romero E, Bartnicki-Garcia S (1977) Properties of chitin synthetase in isolated chitosomes from yeast cells of Mucor rouxii. J Biol Chem 252: 3338–3343

    PubMed  CAS  Google Scholar 

  • Ryder NS, Peberdy JF (1977 a) Chitin synthase activity in dormant conidia of Aspergillus nidulans. FEMS Microbiol Lett 2: 199–201

    CAS  Google Scholar 

  • Ryder NS, Peberdy JF (1977 b) Chitin synthase in Aspergillus nidulans: properties and proteolytic activation. J Gen Microbiol 99: 69–76

    CAS  Google Scholar 

  • Scarborough GA (1975) Isolation and characterization of Neurospora crassa plasma membranes. J Biol Chem 250: 1106–1111

    PubMed  CAS  Google Scholar 

  • Schekman R, Brawley V (1979) Localized deposition of chitin on the yeast cell surface in response to mating pheromone. Proc Natl Acad Sci USA 76: 645–649

    PubMed  CAS  Google Scholar 

  • Seichertová O, Beran K, Holan Z, Pokorny V (1973) The chitin-glucan complex of Saccharomyces cerevisiae. II Location of the complex in the encircling region of the bud scar. Folia Microbiol 18: 207–211

    Google Scholar 

  • Selitrennikoff CP, Sonneborn DR (1976 a) Posttranslational control of de novo cell wall formation during Blastocladiella emersonii zoospore germination. Dev Biol 54: 37–51

    PubMed  CAS  Google Scholar 

  • Selitrennikoff CP, Sonneborn DR (1976b) The last two pathway-specific enzyme activities of hexosamine biosynthesis are present in Blastocladiella emersonii zoospores prior to germination. Biochim Biophys Acta 451: 408–416

    PubMed  CAS  Google Scholar 

  • Selitrennikoff CP, Allin D, Sonneborn DR (1976) Chitin biosynthesis during Blastocladiella zoospore germination : evidence that the hexosamine biosynthetic pathway is post translationally activated during cell differentiation. Proc Natl Acad Sci USA 73: 534–538

    PubMed  CAS  Google Scholar 

  • Sentandreu R, Northcote DH (1969) The formation of buds in yeast. J Gen Microbiol 55: 393–398

    PubMed  CAS  Google Scholar 

  • Sloat BF, Pringle JT (1978) A mutant of yeast defective in cellular morphogenesis. Science 200: 1171–1173

    PubMed  CAS  Google Scholar 

  • Suhadolnik RJ (1970) Nucleoside antibiotics. J Wiley, New York

    Google Scholar 

  • Trinci APJ (1978) Wall and hyphal growth. Sci Prog (New Haven) 65: 75–99

    CAS  Google Scholar 

  • Ulane RE, Cabib E (1974) The activating system of chitin synthetase from Saccharomyces cerevisiae. Purification and properties of an inhibitor of the activating factor. J Biol Chem 249: 3418–3422

    PubMed  CAS  Google Scholar 

  • Ulane RE, Cabib E (1976) The activating system of chitin synthetase from Saccharomyces cerevisiae. Purification and properties of the activating factor. J Biol Chem 251: 3367–3374

    PubMed  CAS  Google Scholar 

  • Van der Valk P, Marchant R, Wessels JGH (1977) Ultrastructural localization of polysaccharides in the wall and septum of the basidiomycete Schizophyllum commune. Exp Mycol 1: 69–82

    Google Scholar 

  • Van Laere AJ, Carlier AR (1978) Synthesis and proteolytic activation of chitin synthetase in Phycomyces blakesleeanus Burgeff. Arch Microbiol 116: 181–184

    Google Scholar 

  • Vermeulen CA, Raeven MBJM, Wessels JGH (1979) Localization of chitin synthase activity in subcellular fractions of Schizophyllum commune protoplasts J Gen Microbiol 114: 87–97

    CAS  Google Scholar 

  • Vrsanska M, Kratky Z, Biely P, Machala S (1979) Chitin structures of the cell walls of synchronously grown virgin cells of Saccharomyces cerevisiae. Z Allg Mikrobiol 19: 357–362

    PubMed  CAS  Google Scholar 

  • Wolf DH, Ehmann C (1978) Isolation of yeast mutants lacking proteinase B activity. FEBS Lett 92: 121–124

    CAS  Google Scholar 

  • Wolf DH, Ehmann C (1979) Studies on a proteinase B mutant of yeast. Eur J Biochem 98: 375–384

    PubMed  CAS  Google Scholar 

  • Wood DA, Hammond JBW (1977) Inhibition of growth and development of Agaricus bisporus by polyoxin D. J Gen Microbiol 98: 625–628

    CAS  Google Scholar 

  • Wright A, Kanegasaki S (1971) Molecular aspects of lipopolysaccharides. Physiol Rev 51: 748–784

    PubMed  CAS  Google Scholar 

  • Yamamoto K, Kawai H, Moriguchi M, Tochikura T (1976) Purification and characterization of yeast UDP-N-acetylglucosamine pyrophosphorylase. Agric Biol Chem 40: 2275–2281

    CAS  Google Scholar 

  • Zubenko GS, Mitchell AP, Jones EW (1979) Septum formation, cell division and sporulation in mutants of yeast deficient in proteinase B. Proc Natl Acad Sci USA 76: 2395–2399

    PubMed  CAS  Google Scholar 

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Cabib, E. (1981). Chitin: Structure, Metabolism, and Regulation of Biosynthesis. In: Tanner, W., Loewus, F.A. (eds) Plant Carbohydrates II. Encyclopedia of Plant Physiology, vol 13 / B. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68234-6_16

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