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Efficacy of Skin Care Products and Different Mixtures of Lipids on Barrier Function

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Dermatopharmacology of Topical Preparations

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Abstract

The skin is a surface organ and is therefore extensively exposed to damaging agents. Damage to the skin barrier seems to initiate a complex cascade of skin reactions which may lead to a skin disease (Figs. 1, 2). Whether or not exposure to a certain agent causes damage to the skin barrier depends on the damaging effect of the agent (exogenous factor), duration and frequency of exposures (Fig. 2), and the individual susceptibility (pre-disposing or endogenous factor, e.g. atopic or aging skin) (Fig. 3). Both exogenous and endogenous factors may vary a lot.

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Authors
  1. L. Halkier-Sørensen
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Editors and Affiliations

  1. Abteilung Biopharmazie Spirig AG, Pharmazeutische Präparate, 4622, Egerkingen, Switzerland

    Bernard Gabard

  2. Institut für Spital-Pharmazie, Universitätskliniken/Kantonspital Basel, Spitalstraße 26, 4031, Basel, Switzerland

    Christian Surber

  3. Klinik für Hautkrankheiten, Klinikum der Friedrich Schiller-Universität Jena, Erfurter Straße 35, 07740, Jena, Germany

    Peter Elsner

  4. Laboratoires Spirig SA, 109, Boulevard d’Haussonville, 5400, Nancy, France

    Pierre Treffel

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Halkier-Sørensen, L. (2000). Efficacy of Skin Care Products and Different Mixtures of Lipids on Barrier Function. In: Gabard, B., Surber, C., Elsner, P., Treffel, P. (eds) Dermatopharmacology of Topical Preparations. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57145-9_21

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  • DOI: https://doi.org/10.1007/978-3-642-57145-9_21

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