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Der Weg ist das Ziel: Dermatologisches Drug Targeting

  • Conference paper
Fortschritte der praktischen Dermatologie und Venerologie

Part of the book series: Fortschritte der praktischen Dermatologie und Venerologie ((DERMATOLOGIE,volume 18))

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Zusammenfassung

Die Behandlung von Hautkrankheiten mit Medikamenten sollte vergleichsweise einfach sein: Ist die Haut mit etwa 1,8 m2 das größte Organ des Menschen und zudem das einzige, das unmittelbar erreichbar ist. Seit Beginn der Entfaltung der Dermatologie als eigenständige medizinische Wissenschaft hat man dies im Rahmen der Therapie berücksichtigt und Wirkstoffe unmittelbar an das Organ herangebracht. Bei etwas näherer Betrachtung stellt man aber rasch zweierlei fest. Zum einen wurden Hauterkrankungen auch versuchsweise von Anfang an systemisch behandelt, also über eine Zufuhr des Wirkstoffs insbesondere durch perorale Applikation, was unvermeidlich damit verbunden ist, dass der Wirkstoff in unterschiedlichem Umfang nicht nur das gegebene Zielorgan Haut erreicht, sondern auch andere, innere Organe. Dies wie derum kann mit einer Vielzahl unerwünschter Wirkungen verbunden sein, die nicht zu erwarten wären, wenn die Haut unmittelbar angesprochen würde.

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Authors
  1. Hans Christian Korting
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Editors and Affiliations

  1. Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstraße 9-11, D-80337, München, Germany

    Gerd Plewig (Prof. Dr. med. Dr. h.c.) & Jörg Prinz (Prof. Dr. med.) (Prof. Dr. med. Dr. h.c.) &  (Prof. Dr. med.)

  2. Kongressbüro Frau Gertrud Hammel, Germany

    Gerd Plewig (Prof. Dr. med. Dr. h.c.) & Jörg Prinz (Prof. Dr. med.) (Prof. Dr. med. Dr. h.c.) &  (Prof. Dr. med.)

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© 2003 Springer-Verlag Berlin Heidelberg

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Korting, H.C. (2003). Der Weg ist das Ziel: Dermatologisches Drug Targeting. In: Plewig, G., Prinz, J. (eds) Fortschritte der praktischen Dermatologie und Venerologie. Fortschritte der praktischen Dermatologie und Venerologie, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55661-6_24

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  • DOI: https://doi.org/10.1007/978-3-642-55661-6_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-43948-6

  • Online ISBN: 978-3-642-55661-6

  • eBook Packages: Springer Book Archive

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