Abstract
We have studied the use of influenza virus to augment the immunogenicity of tumor-transplantation antigens (TTA) isolated from tumor homogenates [1, 2, 3, 4]. The data to be presented here refer to a transplantable SV 40-induced fibrosarcoma in BALB/c mice infected with the WSA strain of mouse-adapted influenza virus [1]. We have obtained similar results with methylcholanthrene-induced fibrosarcomas and a Moloney virus-induced lymphoma of mice. In addition, the Hong Kong strain of influenza virus appears to be as effective as the WSA strain after adaption to growth in mouse cells.
Keywords
- Influenza Virus
- Vesicular Stomatitis Virus
- Tumor Homogenate
- Delay Hypersensitivity Reaction
- Main Tumor Mass
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References
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© 1974 Springer-Verlag Berlin · Heidelberg
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Boone, C.W. (1974). Augmented Immunogenicity of Tumor Cell Homogenates Infected with Influenza Virus. In: Mathé, G., Weiner, R. (eds) Investigation and Stimulation of Immunity in Cancer Patients. Recent Results in Cancer Research, vol 47. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49284-6_57
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DOI: https://doi.org/10.1007/978-3-642-49284-6_57
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-49286-0
Online ISBN: 978-3-642-49284-6
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