Abstract
Carcinoma of the lung is a very common malignant tumor. Histological typing of lung tumors has long been a source of controversy in pathology, in great part due to the marked microscopic heterogeneity of these tumors [1–4]. Although the bronchi and lungs may give rise to a wide variety of histopathologic types of malignant epithelial neoplasms, grading of lung cancer is usually restricted to the two most common types of bronchogenic carcinoma included in the latest WHO classification: squamous cell carcinoma and adenocarcinoma. Neuroendocrine carcinomas of the lung constitute a third major group of lung neoplasms that are amenable to grading, as it has been observed that histologic grading of these tumors appears to correlate with their clinical behavior and prognosis [5]. The fourth major category of bronchogenic carcinoma in the WHO classification, large cell carcinoma, is not subject to grading since it is by definition a high-grade neoplasm.
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© 2013 Springer-Verlag Berlin Heidelberg
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Rao, N., Moran, C., Suster, S. (2013). Tumors of the Lungs and Pleura. In: Damjanov, I., Fan, F. (eds) Cancer Grading Manual. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34516-6_3
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DOI: https://doi.org/10.1007/978-3-642-34516-6_3
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