Abstract
Starting from the basic principles of a Magnetic Particle Spectrometer (MPS), this paper explains the benefits and limitations of conventional spectral representation of the magnetization behavior of magnetic particles. After motivating the advantages of direct m(H) representation for particle analysis, it is shown how this curve, or at least its derivative, which is related to the point spread function, can be derived from the measured data. To illustrate, MPS results for Resovist® are presented, that show experimental evidence of hysteresis in dynamically acquired m(H) curves.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Snyder, S.R., Heinen, U.: Characterization of Magnetic Nanoparticles for Therapy and Diagnostics. Bruker BioSpin Application note 04/11 T128513, http://www.bruker-biospin.com/mps-tech.html , and mps-apps.html
Weizenecker, J., et al.: Particle dynamics of mono-domain particles in MPI. In: First. Int. Workshop on MPI, pp. 3–15. World Scientific Publishing (2010) ISBN 981-4324-67-1
Lu, K., et al.: The impact of filtering direct-feedthrough on the x-space theory of magnetic particle imaging. In: Proceedings of SPIE, paper 7965-90 (2011)
Biederer, S., et al.: A compensation unit for a magnetic particle spectrometer to measure the full magnetization spectrum of SPIO nanoparticles. In: Proceedings of BMT, Freiburg (September 2011); Biomed. Tech. 56(suppl.1) (2011)
Hergt, R., Dutz, S., Zeisberger, M.: Validity limits of the Néel relaxation model of magnetic nanoparticles for hyperthermia. Nanotechnology 21 (2010)
Schmale, I., et al.: Particle distinction within MPI. In: Proceedings of BMT, Rostock (September 2010); Biomed. Tech. 55(suppl.1) (2010)
Croft, L.R., et al.: The x-space formulation of Magnetic Particle Imaging including non-negligible relaxation effects. In: Proceedings of SPIE, paper 7965-93 (2011)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag GmbH Berlin Heidelberg
About this paper
Cite this paper
Schmale, I., Rahmer, J., Gleich, B., Borgert, J., Weizenecker, J. (2012). Point Spread Function Analysis of Magnetic Particles. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_46
Download citation
DOI: https://doi.org/10.1007/978-3-642-24133-8_46
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-24132-1
Online ISBN: 978-3-642-24133-8
eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)