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Alkaloids of Marine Macroalgae

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Natural Products

Abstract

Marine alkaloids have their origins from marine organisms including marine macroalgae. On the other hand, some marine algal alkaloids such as phenylethylamine derivatives were previously isolated from terrestrial plants. The other groups of alkaloids like indole derivatives and halogenated alkaloids are specific for algae. Most of the indole group alkaloids are concentrated in red algae. Green algae are rich of bromine- and chloride-containing alkaloids. These halogenated alkaloids of algae are not present in terrestrial plants and are specific for algae and sea organisms. Marine algae contain 44 alkaloids, consisting of 1 phenylethylamine, 41 indole, and 1 naphthyridine derivates. In the halogenated alkaloid group, there are 25 bromine-containing compounds, among which 7 have chlorine and 5 have sulfur, additionally.

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Abbreviations

ALM:

Almazolone

BRI:

Bromoindole

CAL A:

Callophycin A

CLP:

Caulerpin

CLS:

Caulersin

DOP:

Dopamine

DTC:

Denticin

FRG:

Fragilamide

HAİ:

3-(Hydroxyacetyl)indole

HLI:

Halogenated indoles

HORD:

Hordenine (anhaline)

ICA:

Indole-3-carboxaldehyde

LO A B:

Lophocladine A

MRF A:

Martefragin A

MRT A B:

Martensine A, B

N-ACPEA:

N-Acetylphenylethylamine

N-ACTYR:

N-Acetyltyramine

PEA:

Phenylethylamine

SBRI:

Sulfur-containing bromo indole alkaloids

TYR:

Tyramine

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Acknowledgment

The authors wish to thank M.Sc. E. Karakaş for her assistance in preparation of the manuscript.

Author information

Authors and Affiliations

  1. Turkish Marine Research Foundation (TUDAV), TUDAV, Beykoz, Istanbul, Turkey

    Dr. Kasım Cemal Güven

  2. Department of Chemistry, Zonguldak Karaelmas University, Zonguldak, Turkey

    Burak Coban

  3. Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey

    Ekrem Sezik

  4. Department of Biology, Faculty of Science, 18 Mart University, Çanakkale, Turkey

    Hüseyin Erdugan

  5. Department of Pharmacology, Faculty of Medicine, Yeditepe University, Kayışdağı, Istanbul, Turkey

    Ferda Kaleağasıoğlu

Authors
  1. Dr. Kasım Cemal Güven
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  2. Burak Coban
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  3. Ekrem Sezik
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  4. Hüseyin Erdugan
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  5. Ferda Kaleağasıoğlu
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Corresponding author

Correspondence to Kasım Cemal Güven .

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Editors and Affiliations

  1. Botany Department, M.L. Sukhadia University, Durga Nursery Road, Udaipur, 313001, Rajasthan, India

    Kishan Gopal Ramawat

  2. Institute of Vine and Wine Sciences, Biological-Active Plant Substances Study, University of Bordeaux, 210 Chemin de Leysotte CS 50008, Villenave d'Ornon, 33882, France

    Jean-Michel Mérillon

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Güven, K.C., Coban, B., Sezik, E., Erdugan, H., Kaleağasıoğlu, F. (2013). Alkaloids of Marine Macroalgae. In: Ramawat, K., Mérillon, JM. (eds) Natural Products. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22144-6_179

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