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Wearable and Autonomous Biomedical Devices and Systems for Smart Environment pp 31–54Cite as

Smart Nano-systems for Tumour Cellular Diagnoses and Therapies

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Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 75))

Abstract

The rapid diffusion recently experienced by minimally invasive therapies (MIT) is currently receiving a further significant boost towards modern medicine by the introduction of new nanotechnology-based techniques in the fields of medical imaging and localized therapeutic delivery. The innovative idea of “nanomedicine” is emerging, with its potential to revolutionize the entire disease management process, from diagnosis, through therapy, to serial follow-up, influencing the entire apparatus of medical devices. Nanoparticle contrast agents, in fact, can be targeted to specific cells and tissues of human body, allowing imaging of pathologic processes at a cellular scale. Moreover, nanoparticles are being increasingly involved in the development of new therapeutic approaches (e.g., site-targeted drug delivery, localized hyperthermia, optimized employment of laser and ultrasound power). This chapter reviewes recent nanotechnological applications in the field of non-ionizing cellular imaging and “personalized” therapies, with special focus on innovative strategies for selective cancer detection and treatment. Some very recent experimental results regarding automatic detection of innovative nanoparticle contrast agents on echographic images are also presented.

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Authors and Affiliations

  1. CNR-IFC, National Council of Research, Institute of Clinical Physiology, Lecce, Italy

    Conversano Francesco, Greco Antonio & Casciaro Sergio

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  1. Conversano Francesco
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  2. Greco Antonio
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  3. Casciaro Sergio
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  1. Dipartimento d’Ingegneria dell’innovazione, University of Salento, Lecce, Italy

    Aimé Lay-Ekuakille

  2. School of Engineering and Advanced Technology (SEAT), Massey University (Turitea Campus), Palmerston North, New Zealand

    Subhas Chandra Mukhopadhyay

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Francesco, C., Antonio, G., Sergio, C. (2010). Smart Nano-systems for Tumour Cellular Diagnoses and Therapies. In: Lay-Ekuakille, A., Mukhopadhyay, S.C. (eds) Wearable and Autonomous Biomedical Devices and Systems for Smart Environment. Lecture Notes in Electrical Engineering, vol 75. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15687-8_2

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