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Name Reactions pp 10–11Cite as

Arndt—Eistert homologation

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One-carbon homologation of carboxylic acids using diazomethane.

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References

  1. Arndt, F.; Eistert, B.Ber. 1935, 68, 200–208. Fritz Arndt (1885–1969) was born in Hamburg, Germany. He discovered the Arndt–Eistert homologation at the University of Breslau where he extensively investigated the synthesis of diazomethane and its reactions with aldehydes, ketones, and acid chlorides. Fritz Arndt’s chain-smoking of cigars ensured that his presence in the laboratories was always well advertised. Bernd Eistert (1902–1978), born in Ohlau, Silesia, was Arndt’s Ph.D. student. Eistert later joined I. G. Farbenindustrie, which became BASF after the Allies broke up the conglomerate after WWII.

    Google Scholar 

  2. Podlech, J.; Seebach, D. Angew. Chem., Int. Ed. 1995, 34, 471–472.

    Article  CAS  Google Scholar 

  3. Matthews, J. L.; Braun, C.; Guibourdenche, C.; Overhand, M.; Seebach, D. In Enantioselective Synthesis ofβ-Amino Acids Juaristi, E. ed.; Wiley-VCH: New York, N. Y. 1997, pp 105–126. (Review).

    Google Scholar 

  4. Katritzky, A. R.; Zhang, S.; Fang, Y. Org. Lett. 2000, 2, 3789–3791.

    Article  CAS  Google Scholar 

  5. Vasanthakumar, G.-R.; Babu, V. V. S. Synth. Commun. 2002, 32, 651–657.

    Article  CAS  Google Scholar 

  6. Chakravarty, P. K.; Shih, T. L.; Colletti, S. L.; Ayer, M. B.; Snedden, C.; Kuo, H.; Tyagarajan, S.; Gregory, L.; Zakson-Aiken, M.; Shoop, W. L.; Schmatz, D. M.; Wyvratt, M. J.; Fisher, M. H.; Meinke, P. T. Bioorg. Med. Chem. Lett. 2003, 13, 147–150.

    Article  CAS  Google Scholar 

  7. Gaucher, A.; Dutot, L.; Barbeau, O.; Hamchaoui, W.; Wakselman, M.; Mazaleyrat, J. P. Tetrahedron: Asymmetry 2005, 16, 857–864.

    Article  CAS  Google Scholar 

  8. Podlech, J. In Enantioselective Synthesis ofβ-Amino Acids (2nd Edn.) John Wiley & Sons: Hoboken, NJ, 2005, pp 93–106. (Review).

    Google Scholar 

  9. Spengler, J.; Ruiz-Rodriguez, J.; Burger, K.; Albericio, F. Tetrahedron Lett. 2006, 47, 4557–4560.

    Article  CAS  Google Scholar 

  10. Toyooka, N.; Kobayashi, S.; Zhou, D.; Tsuneki, H.; Wada, T.; Sakai, H.; Nemoto, H.; Sasaoka, T.; Garraffo, H. M.; Spande, T. F.; Daly, J. W. Bioorg. Med. Chem. Lett. 2007, 17, 5872–5875.

    Article  CAS  Google Scholar 

  11. Fuchter, M. J. Arndt–Eistert Homologation. In Name Reactions for Homologations-Part I; Li, J. J., Corey, E. J., Eds.; Wiley & Sons: Hoboken, NJ,2009, pp 336–349. (Review).

    Google Scholar 

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  1. Dept. Discovery Chemistry, Bristol-Myers Squibb Company, 5 Research Parkway, Wallingford, CT 06492, USA

    Dr Jie Jack Li

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  1. Dr Jie Jack Li
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Correspondence to Jie Jack Li .

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Li, J.J. (2009). Arndt—Eistert homologation. In: Name Reactions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01053-8_5

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