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Pathophysiology of Acute Pancreatitis

  • Chapter
Imaging of the Pancreas

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Acute pancreatitis is a common clinical entity that follows a variable course ranging from mild abdominal pain to multisystem organ failure and death. There are numerous known causes of acute pancreatitis, all of which are thought to precipitate the disease by causing acinar cell injury. Although acinar injury may be a common trigger for pancreatitis, the mechanisms linking causal entities to induction of cellular injury remain unclear. Similar to the variability of clinical presentation, the pattern of pancreatic pathology following injury can manifest in many ways including: simple edema, necrosis, pseudocysts, and abscesses.

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Author information

Authors and Affiliations

  1. Department of Surgery, Medical University of South Carolina, Charleston, SC, 29425, USA

    Peter Shamamian MD

  2. Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, 10021, USA

    Peter Kingman MD

  3. Department of Biochemistry, NYU-Langone Medical Center, 550 First Avenue, New York, NY, 10016, USA

    John Mallen-St. Clair BA, MSc & Dafna Bar-Sagi PhD

Authors
  1. Peter Shamamian MD
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  2. Peter Kingman MD
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  3. John Mallen-St. Clair BA, MSc
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  4. Dafna Bar-Sagi PhD
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Editor information

Editors and Affiliations

  1. Department of Radiology Bellevue Hospital, NYU-Langone Medical Center, Room 3W37 462 First Avenue, New York, NY, 10016, USA

    Emil J. Balthazar MD (Professor) (Professor)

  2. Department of Radiology, NYU-Langone Medical Center, 550 First Avenue, New York, NY, 10016, USA

    Alec J. Megibow MD, MPH, FACR (Professor) (Professor)

  3. Department of Radiology Policlinico “GB Rossi”, University of Verona, Piazzale LA Scuro 10, 37134, Verona, Italy

    Roberto Pozzi Mucelli MD (Professor) (Professor)

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© 2009 Springer-Verlag Berlin Heidelberg

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Shamamian, P., Kingman, P., Mallen-St. Clair, J., Bar-Sagi, D. (2009). Pathophysiology of Acute Pancreatitis. In: Balthazar, E.J., Megibow, A.J., Pozzi Mucelli, R. (eds) Imaging of the Pancreas. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68251-6_1

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  • DOI: https://doi.org/10.1007/978-3-540-68251-6_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00281-9

  • Online ISBN: 978-3-540-68251-6

  • eBook Packages: MedicineMedicine (R0)

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