Summary
Cholescintigraphy plays a pivotal role in the evaluation of various biliary tract diseases, particularly when coupled with pharmacological intervention. The physician monitoring the study should be familiar with the most optimal technique for the pharmacological intervention and with conditions and medications that affect gall bladder contraction. It is also important to be aware of the various physiological and pharmacological effects on imaging findings, i.e., not only those findings that are normal but also the undesirable variants [253]. Failure to recognize such effects can lead to incorrect interpretation.
Radionuclide imaging of the liver using the various tracers provides unique functional information, i.e., the functional reserve, presence or absence of hepatocytes/Kupffer’s cells, and RBC pooling. This has been augmented further by the improved resolution with multi-head SPECT systems. Advances in instrumentation such as PET and development of new radiopharmaceuticals, including PET tracers specifically for the evaluation of the liver, will likely expand clinical applications further.
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Kim, C.K., Krynyckyi, B.R., Machac, J. (2006). Digestive System 2: Liver and Biliary Tract. In: Elgazzar, A.H. (eds) The Pathophysiologic Basis of Nuclear Medicine. Springer, Berlin, Heidelberg . https://doi.org/10.1007/978-3-540-47953-6_17
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