Abstract
DNA-binding, base pair-specific fluorescent dyes impart a longitudinal differentiation in mammalian metaphase chromosomes consisting of specific non-periodical patterns of alternating bright and dull bands of characteristic width. Human prometaphase chromosomes exhibit more than 2000 light and dark bands. A very small band at the limit of light microscope resolution contains about 1250 kb (Holmquist 1986 a).
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Schweizer, D., Loidl, J., Hamilton, B. (1987). Heterochromatin and the Phenomenon of Chromosome Banding. In: Hennig, W. (eds) Structure and Function of Eukaryotic Chromosomes. Results and Problems in Cell Differentiation, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47783-9_15
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DOI: https://doi.org/10.1007/978-3-540-47783-9_15
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