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References
American Joint Committee on Cancer: “AJCC Cancer Staging Handbook.” New York: Springer-Verlag, 2002
Ravdin PM, Siminoff LA, Davis GJ et al.: Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer. Journal of Clinical Oncology 2001: 19:980–991
Early Breast Cancer Trialists’ Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. [see comment]. Lancet 1998: 351:1451–1467
Polychemotherapy for early breast cancer: an overview of the randomized trials. Early Breast Cancer Trialists’ Collaborative Group. [see comment]. Lancet 1998: 352:930–942
Goldhirsch A, Wood WC, Gelber RD et al.: Meeting highlights: updated international expert consensus on the primary therapy of early breast cancer. [Review]. Journal of Clinical Oncology 2003: 21:3357–3365
National Institutes of Health Consensus Development Panel.: National Institutes of Health Consensus Development Conference statement: adjuvant therapy for breast cancer, November 1–3, 2000. [Review]. Journal of the National Cancer Institute 2001: Monographs:5–15
International Breast Cancer Study Group.: Endocrine responsiveness and tailoring adjuvant therapy for postmenopausal lymph node-negative breast cancer: a randomized trial. [see comment] [erratum appears in J Natl Cancer Inst 2002 Sep 4;94(17):1339]. Journal of the National Cancer Institute 2002: 94:1054–1065
Zambetti M, Valagussa P, Bonadonna G: Adjuvant cyclophosphamide, methotrexate and fluorouracil in node-negative and estrogen receptor-negative breast cancer. Updated results. Annals of Oncology 1996: 7:481–485
Mansour EG, Gray R, Shatila AH et al.: Survival advantage of adjuvant chemotherapy in high-risk node-negative breast cancer: ten-year analysis—an intergroup study. Journal of Clinical Oncology 1998: 16:3486–3492
Ravdin P, Olivotto I, Speers C et al. Should estrogen receptor negativity alone be an indication for chemotherapy in T1N0 breast cancer? Proc ASCO. Journal of Clinical Oncology 2003: 22:14
Wenger CR, Clark GM: S-phase fraction and breast cancer—a decade of experience. [Review]. Breast Cancer Research and Treatment 1998: 51:255–265
Hutchins L, Green S, Ravdin P et al. CMF versus CAF with and without tamoxifen in highrisk node-negative breast cancer and a natural history follow-up study in low-risk nodenegative patients: first results of intergroup trial 0102. Proc ASCO. Journal of Clinical Oncology 1998:17:1al
Jones S, Clark G, Koleszar G et al. Low proliferative rate of invasive nodenegative breast cancer predicts for a favorable outcome without adjuvant chemotherapy. Proc ASCO. Journal of Clinical Oncology 1999: 18:70a
Goldhirsch A, Glick JH, Gelber RD, Senn HJ: Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. [see comment]. [Review]. Journal of the National Cancer Institute 1998: 90:1601–1608
Daidone MG, Silvestrini R: Prognostic and predictive role of proliferation indices in adjuvant therapy of breast cancer. [Review] [90 refs]. Journal of the National Cancer Institute 2001: Monographs:27–35
Slamon DJ, Clark GM, Wong SG et al.: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987: 235:177–182
Ross JS, Fletcher JA, Linette GP et al.: The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy. [Review]. Oncologist 2003: 8:307–325
Keyomarsi K, Tucker SL, Buchholz TA et al.: Cyclin E and survival in patients with breast cancer. [see comment] [erratum appears in N Engl J Med 2003 Jan 9;348(2):186]. New England Journal of Medicine 2002: 347:1566–1575
Porter PL, Malone KE, Heagerty PJ et al.: Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. [see comment]. Nature Medicine 1997: 3:222–225
Tan P, Cady B, Wanner M et al.: The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer Research 1997: 57:1259–1263
Catzavelos C, Bhattacharya N, Ung YC et al.: Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer. [see comment]. Nature Medicine 1997: 3:227–230
Volpi A, De Paola F, Nanni O et al.: Prognostic significance of biologic markers in nodenegative breast cancer patients: a prospective study. Breast Cancer Research and Treatment 2000: 63:181–192
Barnes DM, Gillett CE: Cyclin D1 in breast cancer. [Review]. Breast Cancer Research and Treatment 1998: 52:1–15
Gruvberger S, Ringner M, Chen Y et al.: Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Research 2001: 61:5979–5984
Janicke F, Prechtl A, Thomssen C et al.: Randomized adjuvant chemotherapy trial in highrisk, lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1. Journal of the National Cancer Institute 2001: 93:913–920
Look MP, van Putten WL, Duffy MJ et al.: Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in 8377 breast cancer patients. Journal of the National Cancer Institute 2002: 94:116–128
Goldhirsch A, Glick JH, Gelber RD et al.: Meeting highlights: International Consensus Panel on the Treatment of Primary Breast Cancer. Seventh International Conference on Adjuvant Therapy of Primary Breast Cancer. [see comment]. [Review]. Journal of Clinical Oncology 2001: 19:3817–3827
van de Vijver MJ, He YD, van’t Veer LJ et al.: A gene-expression signature as a predictor of survival in breast cancer. see comment]. New England Journal of Medicine 2002: 347:1999–2009
Perou CM, Sorlie T, Eisen MB et al.: Molecular portraits of human breast tumours. Nature 2000: 406:747–752
Foulkes WD, Stefansson IM, Chappuis PO et al.: Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. Journal of the National Cancer Institute 2003: 95:1482–1485
Fisher B, Brown AM, Dimitrov NV et al.: Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: results from the National Surgical Adjuvant Breast and Bowel Project B-15. Journal of Clinical Oncology 1990: 8:1483–1496
Jones S, Savin M, Asmar L et al. Three year results of a prospective randomized trial of adjuvant chemotherapy for patients with stage I-III operable, invasive breast cancer comparing four courses of doxorubicin/cyclophosphamide to four courses of docetaxel/cyclophosphamide. Proc ASCO. Journal of Clinical Oncology 2003: 22:15
Bonadonna G, Valagussa P, Moliterni A et al.: Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer: the results of 20 years of follow-up. [see comment]. New England Journal of Medicine 1995: 332:901–906
Martin M, Pienkowski T, Mackey J et al. TAC improves disease free survival and overall survival over FAC in node positive early breast cancer patients, BCIRG 001: 55 months follow-up. Proc San Antonio Breast Cancer Symposium. Breast Cancer Research and Treatment 2003: 82
Citron ML, Berry DA, Cirrincione C et al.: Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. [see comment] [erratum appears in Journal of Clinical Oncology 2003 Jun 1;21(11):2226]. Journal of Clinical Oncology 2003: 21:1431–1439
Levine MN, Bramwell VH, Pritchard KI et al.: Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group. [see comment]. Journal of Clinical Oncology 1998: 16:2651–2658
French Adjuvant Study Group.: Benefit of a high-dose epirubicin regimen in adjuvant chemotherapy for node-positive breast cancer patients with poor prognostic factors: 5-year follow-up results of French Adjuvant Study Group 05 randomized trial. [see comment]. Journal of Clinical Oncology 2001: 19:602–611
Wood WC, Budman DR, Korzun AH et al.: Dose and dose intensity of adjuvant chemotherapy for stage II, node-positive breast carcinoma. see comment] [erratum appears in N Engl J Med 1994 Jul 14;331(2):139]. New England Journal of Medicine 1994: 330:1253–1259
Bontenbal M, Andersson M, Wildiers J et al.: Doxorubicin vs epirubicin, report of a second-line randomized phase II/III study in advanced breast cancer. EORTC Breast Cancer Cooperative Group. British Journal of Cancer 1998: 77:2257–2263
Hortobagyi GN, Yap HY, Kau SW et al.: A comparative study of doxorubicin and epirubicin in patients with metastatic breast cancer. American Journal of Clinical Oncology 1989: 12:57–62
Perez DJ, Harvey VJ, Robinson BA et al.: A randomized comparison of single-agent doxorubicin and epirubicin as first-line cytotoxic therapy in advanced breast cancer. Journal of Clinical Oncology 1991: 9:2148–2152
A prospective randomized phase III trial comparing combination chemotherapy with cyclophosphamide, fluorouracil, and either doxorubicin or epirubicin. French Epirubicin Study Group. Journal of Clinical Oncology 1988: 6:679–688
Valero V, Jones SE, Von Hoff DD et al.: A phase II study of docetaxel in patients with paclitaxel-resistant metastatic breast cancer. Journal of Clinical Oncology 1998: 16:3362–3368
Jones S, Erban J, Overmoyer B et al. Randomized trial comparing docetaxel and paclitaxel in patients with metastatic breast cancer. Proc San Antonio Breast Cancer Symposium. Breast Cancer Research and Treatment 2003: 82:S9
Muss HB, Thor AD, Berry DA et al.: c-erbB-2 expression and response to adjuvant therapy in women with node-positive early breast cancer. [see comment] [erratum appears in N Engl J Med 1994 Jul 21;331(3):211]. New England Journal of Medicine 1994: 330:1260–1266
Thor AD, Berry DA, Budman DR et al.: erbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer. [see comment]. Journal of the National Cancer Institute 1998: 90:1346–1360
Paik S, Bryant J, Tan-Chiu E et al.: HER2 and choice of adjuvant chemotherapy for invasive breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-15. Journal of the National Cancer Institute 2000: 92:1991–1998
Paik S, Bryant J, Park C et al.: erbB-2 and response to doxorubicin in patients with axillary lymph node-positive, hormone receptor-negative breast cancer. [see comment]. Journal of the National Cancer Institute 1998: 90:1361–1370
Di Leo A, Gancberg D, Larsimont D et al.: HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clinical Cancer Research 2002: 8:1107–1116
Di Leo A, Larsimont D, Gancberg D et al.: HER-2 and topo-isomerase IIalpha as predictive markers in a population of node-positive breast cancer patients randomly treated with adjuvant CMF or epirubicin plus cyclophosphamide. Annals of Oncology 2001: 12:1081–1089
Gancberg D, Jarvinen T, Di Leo A et al.: Evaluation of HER-2/NEU protein expression in breast cancer by immunohistochemistry: an interlaboratory study assessing the reproducibility of HER-2/NEU testing. Breast Cancer Research and Treatment 2002: 74:113–120
Jarvinen TA, Tanner M, Barlund M et al.: Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer. Genes, Chromosomes and Cancer 1999: 26:142–150
Jarvinen TA, Tanner M, Rantanen V et al.: Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. American Journal of Pathology 2000: 156:839–847
Pestalozzi BC, Peterson HF, Gelber RD et al.: Prognostic importance of thymidylate synthase expression in early breast cancer. Journal of Clinical Oncology 1997: 15:1923–1931
Romain S, Spyratos F, Descotes F et al.: Prognostic of DNA-synthesizing enzyme activities (thymidine kinase and thymidylate synthase) in 908 T1-T2, N0-N1, M0 breast cancers: a retrospective multicenter study. International Journal of Cancer 2000: 87:860–868
Foekens JA, Romain S, Look MP et al.: Thymidine kinase and thymidylate synthase in advanced breast cancer: response to tamoxifen and chemotherapy. Cancer Research 2001: 61:1421–1425
Bernard-Marty C, Treilleux I, Dumontet C et al.: Microtubule-associated parameters as predictive markers of docetaxel activity in advanced breast cancer patients: results of a pilot study. Clinical Breast Cancer 2002: 3:341–345
Monzo M, Rosell R, Sanchez JJ et al.: Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations. Journal of Clinical Oncology 1999: 17:1786–1793
Giannakakou P, Sackett DL, Kang YK et al.: Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization. Journal of Biological Chemistry 1997: 272:17118–17125
Maeno K, Ito K, Hama Y et al.: Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer. Cancer Letters 2003: 198:89–97
O’Shaughnessy J, Miles D, Vukelja S et al.: Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results. Journal of Clinical Oncology 2002: 20:2812–2823
Valagussa P, Moliterni A, Terenziani M et al.: Second malignancies following CMF-based adjuvant chemotherapy in resectable breast cancer. [see comment]. Annals of Oncology 1994: 5:803–808
Zambetti M, Moliterni A, Materazzo C et al.: Long-term cardiac sequelae in operable breast cancer patients given adjuvant chemotherapy with or without doxorubicin and breast irradiation. Journal of Clinical Oncology 2001: 19:37–43
Piccart MJ, Di Leo A, Beauduin M et al.: Phase III trial comparing two dose levels of epirubicin combined with cyclophosphamide with cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer. Journal of Clinical Oncology 2001: 19:3103–3110
Crump M, Tu D, Shepherd L et al.: Risk of acute leukemia following epirubicin-based adjuvant chemotherapy: a report from the National Cancer Institute of Canada Clinical Trials Group. Journal of Clinical Oncology 2003: 21:3066–3071
Smith RE, Bryant J, DeCillis A et al.: Acute myeloid leukemia and myelodysplastic syndrome after doxorubicin-cyclophosphamide adjuvant therapy for operable breast cancer: the National Surgical Adjuvant Breast and Bowel Project Experience. Journal of Clinical Oncology 2003: 21:1195–1204
Fisher B, Anderson S, Wickerham DL et al.: Increased intensification and total dose of cyclophosphamide in a doxorubicin-cyclophosphamide regimen for the treatment of primary breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-22. Journal of Clinical Oncology 1997: 15:1858–1869
Nabholtz J, Pienkowski T, Mackey J et al. Phase III trial comparing TAC (docetaxel, doxorubicin, cyclophosphamide) with FAC (5-fluorouracil, doxorubicin, cyclophosphamide) in the adjuvant treatment of node positive breast cancer patients: interim analysis of the BCIRG 001. Proc ASCO. Journal of Clinical Oncology 2002: 21:36a
Therasse P, Mauriac L, Welnicka-Jaskiewicz M et al.: Final results of a randomized phase III trial comparing cyclophosphamide, epirubicin, and fluorouracil with a dose-intensified epirubicin and cyclophosphamide + filgrastim as neoadjuvant treatment in locally advanced breast cancer: an EORTC-NCIC-SAKK multicenter study. [Review] [33 refs]. Journal of Clinical Oncology 2003: 21:843–850
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Hamilton, A.L. (2006). Early Breast Cancer (Stage I and Stage II): Tailored Systemic Therapy for Endocrine-Resistant Breast Cancer. In: Piccart, M.J., Hung, MC., Solin, L.J., Cardoso, F., Wood, W.C. (eds) Breast Cancer and Molecular Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-28266-2_16
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