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Cellular and Molecular Toxicology of Nanoparticles pp 99–122Cite as

Toxicity of Metal Oxide Nanoparticles

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1048))

Abstract

In the recent times, nanomaterials are used in many sectors of science, medicine and industry, without revealing its toxic effects. Thus, it is in urgent need for exploring the toxicity along with the application of such useful nanomaterials. Nanomaterials are categorized with a particle size of 1–100 nm. They have gained increasing attention because of their novel properties, including a large specific surface area and high reaction activity. The various fundamental and practical applications of nanomaterials include drug delivery, cell imaging, and cancer therapy. Nanosized semiconductors have their versatile applications in different areas such as catalysts, sensors, photoelectronic devices, highly functional and effective devices etc. Metal oxides contribute in many areas of chemistry, physics and materials science. Mechanism of toxicity of metal oxide nanoparticles can occur by different methods like oxidative stress, co-ordination effects, non-homeostasis effects, genotoxicity and others. Factors that affect the metal oxide nanoparticles were size, dissolution and exposure routes. This chapter will explain elaborately the toxicity of metal oxide nano structures in living beings and their effect in ecosystem.

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Acknowledgement

I am grateful to Chettinad Academy of Research and Education (CARE), Kelambakkam for providing me the infrastructure. My sincere thanks to Mr. Sanjay K Metkar and Ms. Ramalakshmi M, CARE for their immense help and support.

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Authors and Affiliations

  1. Department of Medical Bionanotechnology, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Rajiv Gandhi Salai, Kelambakkam, Kanchipuram, Tamil Nadu, India

    Koyeli Girigoswami

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Correspondence to Koyeli Girigoswami .

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Editors and Affiliations

  1. Zoology Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Quaiser Saquib

  2. Department of Botany and Microbiology, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Mohammad Faisal

  3. Zoology Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Abdulaziz A. Al-Khedhairy

  4. Department of Botany and Microbiology, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Abdulrahman A. Alatar

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Girigoswami, K. (2018). Toxicity of Metal Oxide Nanoparticles. In: Saquib, Q., Faisal, M., Al-Khedhairy, A., Alatar, A. (eds) Cellular and Molecular Toxicology of Nanoparticles. Advances in Experimental Medicine and Biology, vol 1048. Springer, Cham. https://doi.org/10.1007/978-3-319-72041-8_7

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