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Ancillary Studies for Salivary Gland Cytology

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The Milan System for Reporting Salivary Gland Cytopathology

Abstract

A precise cytological classification of salivary gland tumors based on cytomorphology alone is possible for many of the commonly encountered lesions. However, there are challenges for the cytologic diagnosis of some entities. Ancillary tests have become invaluable tools that assist in refining our cytologic diagnoses, and recent advances have improved the diagnostic accuracy of salivary gland fine-needle aspiration (FNA), leading to better patient management. A subset of tumors has been characterized cytogenetically by the presence of specific and recurrent translocations. These translocations and their resulting fusion oncogenes and oncoproteins can be used as diagnostic markers in salivary gland FNA. In this chapter, we describe the ancillary techniques and several currently available ancillary markers for salivary gland FNA.

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Author information

Authors and Affiliations

  1. Department of Pathology, Jewish General Hospital, Montréal, QC, Canada

    Marc Pusztaszeri

  2. Department of Pathology, McGill University, Montréal, QC, Canada

    Marc Pusztaszeri

  3. Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Jorge S. Reis-Filho & Marcia Edelweiss

  4. Department of Pathology and Oncology, Medical Faculty of Porto University, Porto, Portugal

    Fernando Carlos de Lander Schmitt

Authors
  1. Marc Pusztaszeri
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  2. Jorge S. Reis-Filho
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  3. Fernando Carlos de Lander Schmitt
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  4. Marcia Edelweiss
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Corresponding author

Correspondence to Marc Pusztaszeri .

Editor information

Editors and Affiliations

  1. Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA

    William C. Faquin

  2. Unita’ Operativa Istopatologia e Citodiagnostica, Fondazione Policlinico Universitario A. Gemelli, Rome, Roma, Italy

    Esther Diana Rossi

  3. Department of Pathology & Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

    Zubair Baloch

  4. Department of Pathology, Loyola University Medical Center, Maywood, Illinois, USA

    GĂ¼liz A. Barkan

  5. Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy

    Maria P. Foschini

  6. Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA

    Daniel F.I. Kurtycz

  7. Department of Pathology, Jewish General Hospital and McGill University, Montreal, Québec, Canada

    Marc Pusztaszeri

  8. Department of Anatomic and Molecular Pathology, National Laboratory of Health, Dudelange, Luxembourg

    Philippe Vielh

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Pusztaszeri, M., Reis-Filho, J.S., de Lander Schmitt, F.C., Edelweiss, M. (2018). Ancillary Studies for Salivary Gland Cytology. In: Faquin, W., et al. The Milan System for Reporting Salivary Gland Cytopathology . Springer, Cham. https://doi.org/10.1007/978-3-319-71285-7_8

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  • DOI: https://doi.org/10.1007/978-3-319-71285-7_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-71284-0

  • Online ISBN: 978-3-319-71285-7

  • eBook Packages: MedicineMedicine (R0)

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