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Peritoneal Carcinomatosis: Relation to Tumor Deposits

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Book cover Tumor Deposits

Abstract

Peritoneal carcinomatosis is among the poor prognostic factors in different types of malignancies. Cytoreductive surgery and intraperitoneal chemotherapy improved the prognosis of these cases. Mechanisms of peritoneal carcinomatosis are being evaluated. The most favored of these mechanisms is the spillage to the tumoral cells to the peritoneal cavity, either by visceral peritoneal invasion by carcinoma or by traumatic mechanisms, leading to tumor formation at different sites as examples of soil and seeding. The mesenchymal transition of the mesothelial cells seems to be an important contributing factor in this process. However, lymphatic route has also been proposed for early gastric carcinoma cases with peritoneal dissemination. The classification and mechanisms of peritoneal carcinomatosis are presented in this chapter. The possibility of the importance of mechanisms leading to tumor deposit formation elsewhere is discussed in connection with peritoneal carcinomatosis. Different types of morphological variants of tumor deposits are presented.

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Authors and Affiliations

  1. Department of Pathology, Dokuz Eylul University, Inciralti Balcova/Izmir, Turkey

    Sulen Sarioglu

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  1. Sulen Sarioglu
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Sarioglu, S. (2018). Peritoneal Carcinomatosis: Relation to Tumor Deposits. In: Tumor Deposits. Springer, Cham. https://doi.org/10.1007/978-3-319-68582-3_6

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  • DOI: https://doi.org/10.1007/978-3-319-68582-3_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-68581-6

  • Online ISBN: 978-3-319-68582-3

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