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ITP in Childhood: Predictors of Disease Duration

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Book cover Antibody Therapy

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Abstract

Most children with immune thrombocytopenic purpura have a favorable outcome. A small but significant minority have clinically significant chronic ITP that requires ongoing treatment. At presentation, it is not possible to differentiate between the patients who will have a short duration of thrombocytopenia from those who will develop chronic disease. Predictors of ITP outcome would help guide treatment decisions and ultimately improve quality of life. In this chapter, the current body of evidence regarding biomarker and genetic predictors of ITP duration is reviewed.

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Authors and Affiliations

  1. Emory University School of Medicine, Atlanta, GA, USA

    Carolyn M. Bennett MD, MSc

  2. Aflac Cancer and Blood Disorder Center, Children’s Healthcare of Atlanta, 5461 Meridian Mark Road, Suite 400, Atlanta, GA, 30342, USA

    Carolyn M. Bennett MD, MSc

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  1. Carolyn M. Bennett MD, MSc
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Correspondence to Carolyn M. Bennett MD, MSc .

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Editors and Affiliations

  1. Department of Pediatrics, Medical Faculty of the University of Basel, Basel, Switzerland

    Paul Imbach

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Bennett, C.M. (2018). ITP in Childhood: Predictors of Disease Duration. In: Imbach, P. (eds) Antibody Therapy. Springer, Cham. https://doi.org/10.1007/978-3-319-68038-5_16

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  • DOI: https://doi.org/10.1007/978-3-319-68038-5_16

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