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Alcohol and Oral Cancer

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Development of Oral Cancer

Abstract

Alcohol consumption has long been recognised as one of the major risk factors for the development of oral cancer [1]. The establishment of the sole effect of alcohol on the oral mucosa and its link to the development of oral cancer have been considered a significant challenge, principally because alcohol consumption histories are difficult to verify, alter over time, both with respect to beverage type and quantity, and are frequently confounded by tobacco use [2]. This is further explained by the established joint effect of alcohol and tobacco in the development of head and neck cancers [2]. In addition, it can be difficult to obtain reliable information from patients about their alcohol intake where the data on alcohol ingestion is based on a highly subjective estimate provided by patients, and this can be due to the different drinking behaviours, e.g. some may ‘binge’ drink and others have a high daily intake. This chapter will discuss the epidemiological evidence for the role of alcohol in oral cancer, the topical and systemic effects of alcohol, alcohol-related oral carcinogenesis and the association between alcohol-containing mouthwashes and oral cancer risk. It will also outline the health benefits of alcohol moderation and cessation and its role in prevention of human oral cancer.

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Authors and Affiliations

  1. School of Dentistry, University of Western Australia, 17 Monash Avenue, Nedlands, WA, 6009, Australia

    Omar Kujan, Abdulhameed Husain & Camile S. Farah

  2. Australian Centre for Oral Oncology Research & Education, Nedlands, WA, 6009, Australia

    Camile S. Farah

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    Ala-Eddin Al Moustafa

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Kujan, O., Husain, A., Farah, C.S. (2017). Alcohol and Oral Cancer. In: Al Moustafa, AE. (eds) Development of Oral Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-48054-1_5

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