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Antimicrobial/Antifouling Surfaces Obtained by Surface Modification

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Polymers against Microorganisms

Abstract

A major issue in the use of biomaterials in natural environments and in particular in hospitals is related to the microorganism adhesion to the biomaterial surface. In this context, the focus of scientists and biomedical manufacturers turned to the development of coatings capable of resisting bacterial colonization and that can be placed on the surfaces of medical devices.

In this chapter, a variety of concepts and approaches are currently being explored in order to produce materials with anti-infective properties that could be employed for biorelated applications will be described. As will be depicted, the strategies are proposed to either reduce or prevent bacterial adhesion. They basically can be divided into two different methodologies: the first type of methodologies include those strategies that either involve chemical modification to introduce antimicrobial activity or are intrinsically antimicrobial. The second type refers to those methodologies that resort to the formation of micro/nanostructures at the biomaterial surface. This chapter will focus on the first group, i.e., the description of the different strategies to chemically modify the polymer surface to improve their antifouling properties or to provide antimicrobial activity.

However, prior to the description of the different methodologies to fabricate antimicrobial surfaces the approaches that are available in order to modify the chemical composition of a particular surface will be first analyzed.

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  1. Institute of Polymer Science & Technology (ICTP-CSIC), Madrid, Spain

    Juan Rodríguez-Hernández

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Rodríguez-Hernández, J. (2017). Antimicrobial/Antifouling Surfaces Obtained by Surface Modification. In: Polymers against Microorganisms. Springer, Cham. https://doi.org/10.1007/978-3-319-47961-3_5

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