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Unraveling the Chemical Interactions of Fungal Endophytes for Exploitation as Microbial Factories

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Fungal Applications in Sustainable Environmental Biotechnology

Part of the book series: Fungal Biology ((FUNGBIO))

Abstract

Endophytic fungi are a group of mutualistic fungi harbored in plant tissues that are known to provide a plethora of fitness benefits to host plants. It is now firmly established that fungal endophytes have a remarkable capability to produce bioactive secondary metabolites including valuable pharmaceutically relevant agents. Unfortunately, efforts to utilize endophytic fungi as sustainable microbial resources for industrial production of compounds have not yet been successful. Recent studies have revealed that endophytic fungi not only interact with their host plant but also engage in complex communication strategies with associated macro- and microorganisms in order to survive and function in their natural habitat. These multifaceted interactions are difficult to introduce and maintain in vitro under artificial fermentation conditions in the laboratory. Our emerging knowledge on the complex interaction between endophytic fungi and associated organisms as well as the host plants provides a silver lining toward industrial exploitation of endophytes. Herein, we highlight the importance of endophytes (particularly endophytic fungi) in plant-microbe associations and discuss future strategies that might be employed to investigate the chemical communication within endophytic microbial communities, which can lead the way toward sustainable industrial production of important compounds using endophytic fungi.

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Authors and Affiliations

  1. Department of Chemistry and Chemical Biology, Chair of Environmental Chemistry and Analytical Chemistry, Institute of Environmental Research (INFU), TU Dortmund, Otto-Hahn-Str. 6, 44221, Dortmund, Germany

    Wen-Xuan Wang, Souvik Kusari & Michael Spiteller

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  1. Wen-Xuan Wang
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  2. Souvik Kusari
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  3. Michael Spiteller
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Correspondence to Souvik Kusari or Michael Spiteller .

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  1. Faculty of Science and Technology, Department of Natural Sciences, Middlesex University, London, United Kingdom

    Diane Purchase

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Wang, WX., Kusari, S., Spiteller, M. (2016). Unraveling the Chemical Interactions of Fungal Endophytes for Exploitation as Microbial Factories. In: Purchase, D. (eds) Fungal Applications in Sustainable Environmental Biotechnology. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-319-42852-9_14

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