Skip to main content
SpringerLink
Log in

Renovascular Hypertension, Vasculitis, and Aortic Coarctation

Pediatric Hypertension

  • 230 Accesses

Abstract

High blood pressure in children is caused by vascular abnormalities in the aorta such as coarctation or mid-aortic syndrome or in the renal arteries in a significant proportion of cases. The underlying causes are mostly unknown but thought to be an abnormality in the blood vessel wall often called fibromuscular dysplasia. Inflammation in the vessel wall, vasculitis, can also cause hypertension. Vascular abnormalities are important to diagnose as in most cases they are amenable to surgery or angioplasty.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

References

  • Abdulsamea S, Anderson P, Biassoni L, Brennan E, McLaren CA, Marks SD, Roebuck DJ, Selim S, Tullus K (2010) Pre- and postcaptopril renal scintigraphy as a screening test for renovascular hypertension in children. Pediatr Nephrol 25(2):317–322

    Article  PubMed  Google Scholar 

  • Arend WP, Michel BA, Bloch DA, Hunder GG, Calabrese LH, Edworthy SM, Fauci AS, Leavitt RY, Lie JT, Lightfoot RW Jr (1990) The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum 33(8):1129–1134

    Article  CAS  PubMed  Google Scholar 

  • Arora P, Kher V, Singhal MK, Kumar P, Gulati S, Baijal SS, Jain S, Kumar A (1997) Renal artery stenosis in aortoarteritis: spectrum of disease in children and adults. Kidney Blood Press Res 20(5):285–289

    Article  CAS  PubMed  Google Scholar 

  • Bagby SP (1982) Acute responses to arterial pressure and plasma renin activity to converting enzyme inhibition (SQ 20,881) in serially studied dogs with neonatally-induced coarctation hypertension. Hypertension 4(1):146–154

    Article  CAS  PubMed  Google Scholar 

  • Blockmans D (2011) PET in vasculitis. Ann N Y Acad Sci 1228:64–70

    Article  PubMed  Google Scholar 

  • Blondin D, Lanzman R, Schellhammer F, Oels M, Grotemeyer D, Baldus SE, Rump LC, Sandmann W, Voiculescu A (2010) Fibromuscular dysplasia in living renal donors: still a challenge to computed tomographic angiography. Eur J Radiol 75(1):67–71

    Article  CAS  PubMed  Google Scholar 

  • Bofinger A, Hawley C, Fisher P, Daunt N, Stowasser M, Gordon R (2001) Polymorphisms of the renin-angiotensin system in patients with multifocal renal arterial fibromuscular dysplasia. J Hum Hypertens 15(3):185–190

    Article  CAS  PubMed  Google Scholar 

  • Brown BP, Karmazyn B (2014) Renal sonography with Doppler – not shown to be adequate as a screening tool for renovascular hypertension. Pediatr Radiol 44(8):1042–1043

    Article  PubMed  Google Scholar 

  • Brun P, Kchouk H, Mouchet B, Baudouin V, Raynaud A, Loirat C, Azancot-Benisty A (1997) Value of Doppler ultrasound for the diagnosis of renal artery stenosis in children. Pediatr Nephrol 11(1):27–30

    Article  CAS  PubMed  Google Scholar 

  • Castelli PK, Dillman JR, Kershaw DB, Khalatbari S, Stanley JC, Smith EA (2014) Renal sonography with Doppler for detecting suspected pediatric renin-mediated hypertension – is it adequate? Pediatr Radiol 44(1):42–49

    Article  PubMed  Google Scholar 

  • Chhadia S, Cohn RA, Vural G, Donaldson JS (2013) Renal Doppler evaluation in the child with hypertension: a reasonable screening discriminator? Pediatr Radiol 43(12):1549–1556

    Article  PubMed  Google Scholar 

  • Criado E, Izquierdo L, Lujan S, Puras E, del Mar EM (2002) Abdominal aortic coarctation, renovascular, hypertension, and neurofibromatosis. Ann Vasc Surg 16(3):363–367

    Article  PubMed  Google Scholar 

  • Daniels SR, Loggie JM, Schwartz DC, Strife JL, Kaplan S (1985) Systemic hypertension secondary to peripheral vascular anomalies in patients with Williams syndrome. J Pediatr 106(2):249–251

    Article  CAS  PubMed  Google Scholar 

  • Daniels SR, Loggie JM, McEnery PT, Towbin RB (1987) Clinical spectrum of intrinsic renovascular hypertension in children. Pediatrics 80(5):698–704

    CAS  PubMed  Google Scholar 

  • Davis FM, Eliason JL, Ganesh SK, Blatt NB, Stanley JC, Coleman DM (2016) Pediatric nonaortic arterial aneurysms. J Vasc Surg 63(2):466–476

    Article  PubMed  Google Scholar 

  • Deal JE, Snell MF, Barratt TM, Dillon MJ (1992) Renovascular disease in childhood. J Pediatr 121(3):378–384

    Article  CAS  PubMed  Google Scholar 

  • Dillon MJ, Ryness JM (1975) Plasma renin activity and aldosterone concentration in children. Br Med J 4(5992):316–319

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dondi M, Fanti S, Monetti N (1993) Captopril renal scintigraphy: a viewpoint. J Nucl Biol Med 37(4):259–263

    CAS  PubMed  Google Scholar 

  • Donnai D, Karmiloff-Smith A (2000) Williams syndrome: from genotype through to the cognitive phenotype. Am J Med Genet 97(2):164–171

    Article  CAS  PubMed  Google Scholar 

  • Duprey A, Chavent B, Meyer-Bisch V, Varin T, Albertini JN, Favre JP, Barral X, Ricco JB (2016) Editor’s choice – ex vivo renal artery repair with kidney autotransplantation for renal artery branch aneurysms: long-term results of sixty-seven procedures. Eur J Vasc Endovasc Surg 51(6):872–879

    Article  CAS  PubMed  Google Scholar 

  • Eklof H, Ahlstrom H, Magnusson A, Andersson LG, Andren B, Hagg A, Bergqvist D, Nyman R (2006) A prospective comparison of duplex ultrasonography, captopril renography, MRA, and CTA in assessing renal artery stenosis. Acta Radiol 47(8):764–774

    Article  CAS  PubMed  Google Scholar 

  • Eliason JL, Coleman DM, Criado E, Kershaw DB, Blatt NB, Williams DM, Dasika NL, Cho KJ, Stanley JC (2016) Remedial operations for failed endovascular therapy of 32 renal artery stenoses in 24 children. Pediatr Nephrol 31(5):809–817

    Article  PubMed  Google Scholar 

  • Estepa R, Gallego N, Orte L, Belanger A, Aracil E, Ortuno J (2001) Pediatric renovascular hypertension. Pediatr Nephrol 16(6):529–531

    CAS  PubMed  Google Scholar 

  • Fommei E, Mezzasalma L, Ghione S (1990) Captopril radionuclide test in renovascular hypertension. A European multicenter study. Contrib Nephrol 79:205–210

    Article  CAS  PubMed  Google Scholar 

  • Forsey J, Dhandayuthapani G, Hamilton M, Martin R, Tizard E, Ramanan A (2011) Takayasu arteritis: key clinical factors for early diagnosis. Arch Dis Child Educ Pract Ed 96(5):176–182

    Article  CAS  PubMed  Google Scholar 

  • Fossali E, Signorini E, Intermite RC, Casalini E, Lovaria A, Maninetti MM, Rossi LN (2000) Renovascular disease and hypertension in children with neurofibromatosis. Pediatr Nephrol 14(8–9):806–810

    Article  CAS  PubMed  Google Scholar 

  • Ghirardo G, De FM, Vidal E, Vidoni A, Ramondo G, Benetti E, Motta R, Ferraro A, Zanon GF, Miotto D, Murer L (2014) Transplant renal artery stenosis in children: risk factors and outcome after endovascular treatment. Pediatr Nephrol 29(3):461–467

    Article  PubMed  Google Scholar 

  • Gill DG, de Mendes CB, Cameron JS, Joseph MC, Ogg CS, Chantler C (1976) Analysis of 100 children with severe and persistent hypertension. Arch Dis Child 51(12):951–956

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Goonasekera CD, Shah V, Wade AM, Dillon MJ (2002) The usefulness of renal vein renin studies in hypertensive children: a 25-year experience. Pediatr Nephrol 17(11):943–949

    Article  PubMed  Google Scholar 

  • Green R, Gu X, Kline-Rogers E, Froehlich J, Mace P, Gray B, Katzen B, Olin J, Gornik HL, Cahill AM, Meyers KE (2016) Differences between the pediatric and adult presentation of fibromuscular dysplasia: results from the US registry. Pediatr Nephrol 31(4):641–650

    Article  PubMed  Google Scholar 

  • Gulati A, Bagga A (2010) Large vessel vasculitis. Pediatr Nephrol 25(6):1037–1048

    Article  PubMed  Google Scholar 

  • Hacklander T, Mertens H, Stattaus J, Lurken M, Lerch H, Altenburg A, Rautenbach J, Cramer BM (2004) Evaluation of renovascular hypertension: comparison of functional MRI and contrast-enhanced MRA with a routinely performed renal scintigraphy and DSA. J Comput Assist Tomogr 28(6):823–831

    Article  PubMed  Google Scholar 

  • Hamilton JR (1998) Surgical controversies: coarctation. Cardiol Young 8(1):50–53

    Article  CAS  PubMed  Google Scholar 

  • Hari P, Bagga A, Srivastava RN (2000) Sustained hypertension in children. Indian Pediatr 37(3):268–274

    CAS  PubMed  Google Scholar 

  • Hegde S, Coulthard MG (2007) Follow-up of early unilateral nephrectomy for hypertension. Arch Dis Child Fetal Neonatal Ed 92(4):F305–F306

    Article  PubMed  Google Scholar 

  • Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, Eagle KA, Hermann LK, Isselbacher EM, Kazerooni EA, Kouchoukos NT, Lytle BW, Milewicz DM, Reich DL, Sen S, Shinn JA, Svensson LG, Williams DM (2010) ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. J Am Coll Cardiol 55(14):e27–e129

    Article  PubMed  Google Scholar 

  • Humbert J, Roussey-Kesler G, Guerin P, LeFrancois T, Connault J, Chenouard A, Warin-Fresse K, Salomon R, Bruel A, Allain-Launay E (2015) Diagnostic and medical strategy for renovascular hypertension: report from a monocentric pediatric cohort. Eur J Pediatr 174(1):23–32

    Article  CAS  PubMed  Google Scholar 

  • Imamura H, Isobe M, Takenaka H, Kinoshita O, Sekiguchi M, Ohta M (1998) Successful stenting of bilateral renal artery stenosis due to fibromuscular dysplasia assessed by use of pressure guidewire technique: a case report. Angiology 49(1):69–74

    Article  CAS  PubMed  Google Scholar 

  • Ing FF, Goldberg B, Siegel DH, Trachtman H, Bierman FZ (1995) Arterial stents in the management of neurofibromatosis and renovascular hypertension in a pediatric patient: case report of a new treatment modality. Cardiovasc Intervent Radiol 18(6):414–418

    Article  CAS  PubMed  Google Scholar 

  • Ishijima H, Ishizaka H, Sakurai M, Ito K, Endo K (1997) Partial renal embolization for pediatric renovascular hypertension secondary to fibromuscular dysplasia. Cardiovasc Intervent Radiol 20(5):383–386

    Article  CAS  PubMed  Google Scholar 

  • Kadian-Dodov D, Gornik HL, Gu X, Froehlich J, Bacharach JM, Chi YW, Gray BH, Jaff MR, Kim ES, Mace P, Sharma A, Kline-Rogers E, White C, Olin JW (2016) Dissection and aneurysm in patients with fibromuscular dysplasia: findings from the U.S. Registry for FMD. J Am Coll Cardiol 68(2):176–185

    Article  PubMed  Google Scholar 

  • Kari JA, Roebuck DJ, McLaren CA, Davis M, Dillon MJ, Hamilton G, Shroff R, Marks SD, Tullus K (2014) Angioplasty for renovascular hypertension in 78 children. Arch Dis Child. 100:474–478

    Google Scholar 

  • Kavey RE, Cotton JL, Blackman MS (1990) Atenolol therapy for exercise-induced hypertension after aortic coarctation repair. Am J Cardiol 66(17):1233–1236

    Article  CAS  PubMed  Google Scholar 

  • Kenny D, Polson JW, Martin RP, Paton JF, Wolf AR (2011) Hypertension and coarctation of the aorta: an inevitable consequence of developmental pathophysiology. Hypertens Res 34(5):543–547

    Article  PubMed  Google Scholar 

  • Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS (1994) Takayasu arteritis. Ann Intern Med 120(11):919–929

    Article  CAS  PubMed  Google Scholar 

  • Konig K, Gellermann J, Querfeld U, Schneider MB (2006) Treatment of severe renal artery stenosis by percutaneous transluminal renal angioplasty and stent implantation: review of the pediatric experience: apropos of two cases. Pediatr Nephrol 21(5):663–671

    Article  PubMed  Google Scholar 

  • Kurian J, Epelman M, Darge K, Meyers K, Nijs E, Hellinger JC (2013) The role of CT angiography in the evaluation of pediatric renovascular hypertension. Pediatr Radiol 43(4):490–501

    Article  PubMed  Google Scholar 

  • Kurien A, John PR, Milford DV (1997) Hypertension secondary to progressive vascular neurofibromatosis. Arch Dis Child 76(5):454–455

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ladapo TA, Gajjar P, McCulloch M, Scott C, Numanoglu A, Nourse P (2015) Impact of revascularization on hypertension in children with Takayasu’s arteritis-induced renal artery stenosis: a 21-year review. Pediatr Nephrol 30(8):1289–1295

    Article  PubMed  Google Scholar 

  • Li JC, Wang L, Jiang YX, Dai Q, Cai S, Lv K, Qi ZH (2006) Evaluation of renal artery stenosis with velocity parameters of Doppler sonography. J Ultrasound Med 25(6):735–742

    Article  PubMed  Google Scholar 

  • Liang CD, Wu CJ, Fang CY, Ko SF (2002) Endovascular stent placement for management of total renal artery occlusion in a child. J Invasive Cardiol 14(1):32–35

    PubMed  Google Scholar 

  • Marks SD, Gullett AM, Brennan E, Tullus K, Jaureguiberry G, Klootwijk E, Stanescu HC, Kleta R, Woolf AS (2011) Renal FMD may not confer a familial hypertensive risk nor is it caused by ACTA2 mutations. Pediatr Nephrol 26(10):1857–1861

    Article  PubMed  Google Scholar 

  • McCrindle BW (1999) Coarctation of the aorta. Curr Opin Cardiol 14(5):448–452

    Article  CAS  PubMed  Google Scholar 

  • McCulloch M, Andronikou S, Goddard E, Sinclair P, Lawrenson J, Mandelstam S, Beningfield SJ, Millar AJ (2003) Angiographic features of 26 children with Takayasu’s arteritis. Pediatr Radiol 33(4):230–235

    Article  PubMed  Google Scholar 

  • McLaren CA, Roebuck DJ (2003) Interventional radiology for renovascular hypertension in children. Tech Vasc Interv Radiol 6(4):150–157

    Article  PubMed  Google Scholar 

  • McTaggart SJ, Gulati S, Walker RG, Powell HR, Jones CL (2000) Evaluation and long-term outcome of pediatric renovascular hypertension. Pediatr Nephrol 14(10–11):1022–1029

    Article  CAS  PubMed  Google Scholar 

  • Miller JM, Rochitte CE, Dewey M, Arbab-Zadeh A, Niinuma H, Gottlieb I, Paul N, Clouse ME, Shapiro EP, Hoe J, Lardo AC, Bush DE, de Roos RA, Cox C, Brinker J, Lima JA (2008) Diagnostic performance of coronary angiography by 64-row CT. N Engl J Med 359(22):2324–2336

    Article  CAS  PubMed  Google Scholar 

  • Min PK, Park S, Jung JH, Ko YG, Choi D, Jang Y, Shim WH (2005) Endovascular therapy combined with immunosuppressive treatment for occlusive arterial disease in patients with Takayasu’s arteritis. J Endovasc Ther 12(1):28–34

    Article  PubMed  Google Scholar 

  • Minson S, McLaren CA, Roebuck DJ, Tullus K (2012) Infantile midaortic syndrome with aortic occlusion. Pediatr Nephrol 27(2):321–324

    Article  PubMed  Google Scholar 

  • Minty I, Lythgoe MF, Gordon I (1993) Hypertension in paediatrics: can pre- and post-captopril technetium-99m dimercaptosuccinic acid renal scans exclude renovascular disease? Eur J Nucl Med 20(8):699–702

    Article  CAS  PubMed  Google Scholar 

  • Moltzer E, Mattace Raso FU, Karamermer Y, Boersma E, Webb GD, Simoons ML, Danser AH, van den Meiracker AH, Roos-Hesselink JW (2010) Comparison of Candesartan versus Metoprolol for treatment of systemic hypertension after repaired aortic coarctation. Am J Cardiol 105(2):217–222

    Article  CAS  PubMed  Google Scholar 

  • Neymark E, LaBerge JM, Hirose R, Melzer JS, Kerlan RK Jr, Wilson MW, Gordon RL (2000) Arteriographic detection of renovascular disease in potential renal donors: incidence and effect on donor surgery. Radiology 214(3):755–760

    Article  CAS  PubMed  Google Scholar 

  • Ng CS, de Bruyn BR, Gordon I (1997) The investigation of renovascular hypertension in children: the accuracy of radio-isotopes in detecting renovascular disease. Nucl Med Commun 18(11):1017–1028

    Article  CAS  PubMed  Google Scholar 

  • Olin JW, Sealove BA (2011) Diagnosis, management, and future developments of fibromuscular dysplasia. J Vasc Surg 53(3):826–836

    Article  PubMed  Google Scholar 

  • Olin JW, Froehlich J, Gu X, Bacharach JM, Eagle K, Gray BH, Jaff MR, Kim ES, Mace P, Matsumoto AH, McBane RD, Kline-Rogers E, White CJ, Gornik HL (2012) The United States Registry for fibromuscular dysplasia: results in the first 447 patients. Circulation 125(25):3182–3190

    Article  PubMed  Google Scholar 

  • Olin JW, Gornik HL, Bacharach JM, Biller J, Fine LJ, Gray BH, Gray WA, Gupta R, Hamburg NM, Katzen BT, Lookstein RA, Lumsden AB, Newburger JW, Rundek T, Sperati CJ, Stanley JC (2014) Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association. Circulation 129(9):1048–1078

    Article  PubMed  Google Scholar 

  • O’Neill JA Jr, Berkowitz H, Fellows KJ, Harmon CM (1995) Midaortic syndrome and hypertension in childhood. J Pediatr Surg 30(2):164–171

    Article  PubMed  Google Scholar 

  • O’Sullivan JJ, Derrick G, Darnell R (2002) Prevalence of hypertension in children after early repair of coarctation of the aorta: a cohort study using casual and 24 hour blood pressure measurement. Heart 88(2):163–166

    Article  PubMed  PubMed Central  Google Scholar 

  • Ozen S, Ruperto N, Dillon MJ, Bagga A, Barron K, Davin JC, Kawasaki T, Lindsley C, Petty RE, Prieur AM, Ravelli A, Woo P (2006) EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis 65(7):936–941

    Article  CAS  PubMed  Google Scholar 

  • Ozen S, Pistorio A, Iusan SM, Bakkaloglu A, Herlin T, Brik R, Buoncompagni A, Lazar C, Bilge I, Uziel Y, Rigante D, Cantarini L, Hilario MO, Silva CA, Alegria M, Norambuena X, Belot A, Berkun Y, Estrella AI, Olivieri AN, Alpigiani MG, Rumba I, Sztajnbok F, Tambic-Bukovac L, Breda L, Al-Mayouf S, Mihaylova D, Chasnyk V, Sengler C, Klein-Gitelman M, Djeddi D, Nuno L, Pruunsild C, Brunner J, Kondi A, Pagava K, Pederzoli S, Martini A, Ruperto N (2010) EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: final classification criteria. Ann Rheum Dis 69(5):798–806

    Article  PubMed  Google Scholar 

  • Palmerini T, Biondi-Zoccai G, Della RD, Stettler C, Sangiorgi D, D’Ascenzo F, Kimura T, Briguori C, Sabate M, Kim HS, De WA, Kedhi E, Smits PC, Kaiser C, Sardella G, Marullo A, Kirtane AJ, Leon MB, Stone GW (2012) Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis. Lancet 379(9824):1393–1402

    Article  CAS  PubMed  Google Scholar 

  • Panayiotopoulos YP, Tyrrell MR, Koffman G, Reidy JF, Haycock GB, Taylor PR (1996) Mid-aortic syndrome presenting in childhood. Br J Surg 83(2):235–240

    Article  CAS  PubMed  Google Scholar 

  • Pannier-Moreau I, Grimbert P, Fiquet-Kempf B, Vuagnat A, Jeunemaitre X, Corvol P, Plouin PF (1997) Possible familial origin of multifocal renal artery fibromuscular dysplasia. J Hypertens 15(12 Pt 2):1797–1801

    Article  CAS  PubMed  Google Scholar 

  • Pedersen TA, Munk K, Andersen NH, Lundorf E, Pedersen EB, Hjortdal VE, Emmertsen K (2011) High long-term morbidity in repaired aortic coarctation: weak association with residual arch obstruction. Congenit Heart Dis 6(6):573–582

    Article  PubMed  Google Scholar 

  • Perdu J, Gimenez-Roqueplo AP, Boutouyrie P, Beaujour S, Laloux B, Nau V, Fiquet-Kempf B, Emmerich J, Tichet J, Plouin PF, Laurent S, Jeunemaitre X (2006) Alpha1-antitrypsin gene polymorphisms are not associated with renal arterial fibromuscular dysplasia. J Hypertens 24(4):705–710

    Article  CAS  PubMed  Google Scholar 

  • Perdu J, Boutouyrie P, Bourgain C, Stern N, Laloux B, Bozec E, Azizi M, Bonaiti-Pellie C, Plouin PF, Laurent S, Gimenez-Roqueplo AP, Jeunemaitre X (2007) Inheritance of arterial lesions in renal fibromuscular dysplasia. J Hum Hypertens 21(5):393–400

    CAS  PubMed  Google Scholar 

  • Poloskey SL, Kim ES, Sanghani R, Al-Quthami AH, Arscott P, Moran R, Rigelsky CM, Gornik HL (2012) Low yield of genetic testing for known vascular connective tissue disorders in patients with fibromuscular dysplasia. Vasc Med 17(6):371–378

    Article  PubMed  Google Scholar 

  • Roegel JC, Heinrich E, De JW, Stephan D, Charpentier A, Eisenmann B, Imbs JL (1998) Vascular and neuroendocrine components in altered blood pressure regulation after surgical repair of coarctation of the aorta. J Hum Hypertens 12(8):517–525

    Article  CAS  PubMed  Google Scholar 

  • Sandmann W, Dueppers P, Pourhassan S, Voiculescu A, Klee D, Balzer KM (2014) Early and long-term results after reconstructive surgery in 42 children and two young adults with renovascular hypertension due to fibromuscular dysplasia and middle aortic syndrome. Eur J Vasc Endovasc Surg 47(5):509–516

    Article  CAS  PubMed  Google Scholar 

  • Schievink WI, Bjornsson J, Parisi JE, Prakash UB (1994) Arterial fibromuscular dysplasia associated with severe alpha 1-antitrypsin deficiency. Mayo Clin Proc 69(11):1040–1043

    Article  CAS  PubMed  Google Scholar 

  • Seirafi PA, Warner KG, Geggel RL, Payne DD, Cleveland RJ (1998) Repair of coarctation of the aorta during infancy minimizes the risk of late hypertension. Ann Thorac Surg 66(4):1378–1382

    Article  CAS  PubMed  Google Scholar 

  • Sethna CB, Kaplan BS, Cahill AM, Velazquez OC, Meyers KE (2008) Idiopathic mid-aortic syndrome in children. Pediatr Nephrol 23(7):1135–1142

    Article  PubMed  Google Scholar 

  • Shahdadpuri J, Frank R, Gauthier BG, Siegel DN, Trachtman H (2000) Yield of renal arteriography in the evaluation of pediatric hypertension. Pediatr Nephrol 14(8–9):816–819

    Article  CAS  PubMed  Google Scholar 

  • Shroff R, Roebuck DJ, Gordon I, Davies R, Stephens S, Marks S, Chan M, Barkovics M, McLaren CA, Shah V, Dillon MJ, Tullus K (2006) Angioplasty for renovascular hypertension in children: 20-year experience. Pediatrics 118(1):268–275

    Article  PubMed  Google Scholar 

  • Slovut DP, Olin JW (2004) Fibromuscular dysplasia. N Engl J Med 350(18):1862–1871

    Article  CAS  PubMed  Google Scholar 

  • Stadermann MB, Montini G, Hamilton G, Roebuck DJ, McLaren CA, Dillon MJ, Marks SD, Tullus K (2010) Results of surgical treatment for renovascular hypertension in children: 30 year single centre experience. Nephrol Dial Transplant 25(3):807–813

    Article  PubMed  Google Scholar 

  • Stanley JC, Zelenock GB, Messina LM, Wakefield TW (1995) Pediatric renovascular hypertension: a thirty-year experience of operative treatment. J Vasc Surg 21(2):212–226

    Article  CAS  PubMed  Google Scholar 

  • Stanley JC, Criado E, Upchurch GR Jr, Brophy PD, Cho KJ, Rectenwald JE, Kershaw DB, Williams DM, Berguer R, Henke PK, Wakefield TW (2006) Pediatric renovascular hypertension: 132 primary and 30 secondary operations in 97 children. J Vasc Surg 44(6):1219–1228

    Article  PubMed  Google Scholar 

  • Tabbutt S, Nicolson SC, Adamson PC, Zhang X, Hoffman ML, Wells W, Backer CL, McGowan FX, Tweddell JS, Bokesch P, Schreiner M (2008) The safety, efficacy, and pharmacokinetics of esmolol for blood pressure control immediately after repair of coarctation of the aorta in infants and children: a multicenter, double-blind, randomized trial. J Thorac Cardiovasc Surg 136(2):321–328

    Article  CAS  PubMed  Google Scholar 

  • Tanaka F, Kawakami A, Iwanaga N, Tamai M, Izumi Y, Aratake K, Arima K, Kamachi M, Nakamura H, Huang M, Ida H, Origuchi T, Eguchi K (2006) Infliximab is effective for Takayasu arteritis refractory to glucocorticoid and methotrexate. Intern Med 45(5):313–316

    Article  PubMed  Google Scholar 

  • Teigen CL, Mitchell SE, Venbrux AC, Christenson MJ, McLean RH (1992) Segmental renal artery embolization for treatment of pediatric renovascular hypertension. J Vasc Interv Radiol 3(1):111–117

    Article  CAS  PubMed  Google Scholar 

  • Tse Y, Marks SD, Brennan E, Hamilton G, McLaren CA, Roebuck DJ, Tullus K (2012) Renal artery revascularisation can restore kidney function with absent radiotracer uptake. Pediatr Nephrol 27(11):2153–2157

    Article  PubMed  Google Scholar 

  • Tullus K (2013) Renovascular hypertension-is it fibromuscular dysplasia or Takayasu arteritis. Pediatr Nephrol 28(2):191–196

    Article  PubMed  Google Scholar 

  • Tullus K (2015) Management of the renovascular disease in children with Takayasu arteritis. Pediatr Nephrol 30(8):1213–1216

    Article  PubMed  Google Scholar 

  • Tullus K, Brennan E, Hamilton G, Lord R, McLaren CA, Marks SD, Roebuck DJ (2008) Renovascular hypertension in children. Lancet 371(9622):1453–1463

    Article  CAS  PubMed  Google Scholar 

  • Tullus K, Roebuck DJ, McLaren CA, Marks SD (2010) Imaging in the evaluation of renovascular disease. Pediatr Nephrol 25(6):1049–1056

    Article  PubMed  Google Scholar 

  • Vasbinder GB, Nelemans PJ, Kessels AG, Kroon AA, Maki JH, Leiner T, Beek FJ, Korst MB, Flobbe K, de Haan MW, van Zwam WH, Postma CT, Hunink MG, de Leeuw PW, van Engelshoven JM (2004) Accuracy of computed tomographic angiography and magnetic resonance angiography for diagnosing renal artery stenosis. Ann Intern Med 141(9):674–682

    Article  PubMed  Google Scholar 

  • Vo NJ, Hammelman BD, Racadio JM, Strife CF, Johnson ND, Racadio JM (2006) Anatomic distribution of renal artery stenosis in children: implications for imaging. Pediatr Radiol 36(10):1032–1036

    Article  PubMed  Google Scholar 

  • Walhout RJ, Plokker HW, Meijboom EJ, Doevendans PA (2008) Advances in the management and surveillance of patients with aortic coarctation. Acta Cardiol 63(6):771–782

    Article  PubMed  Google Scholar 

  • Willsher A, Roebuck DJ, Ng J, Ganesan V (2013) How commonly do children with complex cerebral arteriopathy have renovascular disease? Dev Med Child Neurol 55(4):335–340

    Article  PubMed  Google Scholar 

  • Wong H, Hadi M, Khoury T, Geary D, Rubin B, Filler G (2006) Management of severe hypertension in a child with tuberous sclerosis-related major vascular abnormalities. J Hypertens 24(3):597–599

    Article  CAS  PubMed  Google Scholar 

  • Wong D, Benson LN, Van Arsdell GS, Karamlou T, McCrindle BW (2008) Balloon angioplasty is preferred to surgery for aortic coarctation. Cardiol Young 18(1):79–88

    Article  PubMed  Google Scholar 

  • Wyszynska T, Cichocka E, Wieteska-Klimczak A, Jobs K, Januszewicz P (1992) A single pediatric center experience with 1025 children with hypertension. Acta Paediatr 81(3):244–246

    Article  CAS  PubMed  Google Scholar 

  • Yagi S, Kramsch DM, Madoff IM, Hollander W (1968) Plasma renin activity in hypertension associated with coarctation of the aorta. Am J Physiol 215(3):605–610

    CAS  PubMed  Google Scholar 

  • Ye C, Yin H, Lin Y, Zhou L, Ye R, Li X, Han A, Wang S (2012) Abdominal aorta aneurysms in children: single-center experience of six patients. Ann Thorac Surg 93(1):201–205

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK

    Kjell Tullus & Wesley Hayes

Authors
  1. Kjell Tullus
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wesley Hayes
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kjell Tullus .

Editor information

Editors and Affiliations

  1. Division of Nephrology, Seattle Children's Hospital, Seattle, Washington, USA

    Joseph Flynn

  2. Massachusetts General Hospital, Boston, Massachusetts, USA

    Julie R. Ingelfinger

  3. Arkansas Children's Hospital, University of Arkansas Medical Science, Little Rock, Arkansas, USA

    Karen Redwine

Section Editor information

  1. Division of Nephrology, Seattle Children’s Hospital, 4800 Sand Point Way NE, 98105, Seattle, WA, USA

    Joseph T. Flynn MD, MS

  2. Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA

    Joseph T. Flynn MD, MS

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing AG

About this entry

Cite this entry

Tullus, K., Hayes, W. (2016). Renovascular Hypertension, Vasculitis, and Aortic Coarctation. In: Flynn, J., Ingelfinger, J., Redwine, K. (eds) Pediatric Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-319-31420-4_24-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-31420-4_24-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-31420-4

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Chapter history

  1. Latest

    Renovascular Hypertension, Vasculitis, and Aortic Coarctation
    Published:
    09 September 2022

    DOI: https://doi.org/10.1007/978-3-319-31420-4_24-2

  2. Original

    Renovascular Hypertension, Vasculitis, and Aortic Coarctation
    Published:
    13 December 2016

    DOI: https://doi.org/10.1007/978-3-319-31420-4_24-1

Search

Navigation