Abstract
Nonrecurrent inferior laryngeal nerve is a rare (NRLN), asymptomatic anomaly. Given the consequences of iatrogenic injury, intimate knowledge of all possible anatomic variations and correlated vascular aberrancies is critical to thyroid surgeons. With awareness and meticulous dissection, injury can be avoided.
The routine use of intraoperative nerve monitoring with an algorithm for identifying the nonrecurrent inferior laryngeal nerve may be associated with reduced nerve injury rates. A technique of stimulating both the proximal vagus nerve at the upper border of the thyroid cartilage and the distal vagus nerve at the fourth tracheal ring allows for the reliable intraoperative identification of an NRLN.
The surgical approach is predicated on the preoperative absence or knowledge of the vascular anomaly associated with an NRLN and the surgical practice of the operating surgeon in terms of distal or proximal identification of the RLN as it relates to its insertion in the larynx. Each of these factors will impact upon the successful management of this rare anatomic variant.
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References
Avisse C, Marcus C, Delattre JF, et al. Right nonrecurrent inferior laryngeal nerve and arteria lusoria: the diagnostic and therapeutic implications of an anatomic anomaly. Review of 17 cases. Surg Radiol Anat. 1998;20(3):227–32.
Hart J. A case of irregular origin and course of the right subclavian and right inferior laryngeal nerve: with remarks. Edin Med Surg J. 1826;25:286.
Hilton J. On the distribution and probable function of the superior and recurrent laryngeal nerves: as demonstrated by dissection in the human subject. Guys Hosp Rep. 1837;2:514.
Pemberton JD, Beaver MG. Anomaly of the right recurrent laryngeal nerve. Surg Gynecol Obstet. 1932;54:594–5.
Berlin D. The recurrent laryngeal nerves in relation of the normal thyroid gland. Surg Gynecol Obstet. 1935;60:19–26.
Coady MA, Adler F, Davila JJ, Gahtan V. Nonrecurrent laryngeal nerve during carotid artery surgery: case report and literature review. J Vasc Surg. 2000;32(1):192–6.
Doherty GM, Mulholland MW, Lillemoe KD, Maier RV, Simeone DM, Upchurch GR. Greenfield’s Surgery: scientific principles and practice. 5th ed. Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2010.
Epstein DA, Debord JR. Abnormalities associated with aberrant right subclavian arteries—a case report. Vasc Endovascular Surg. 2002;36(4):297–303.
Bayford D. Account of singular case of obstructive deglutition. Mem Med Soc Lond. 1794;2:271–82.
Henry JF, Audiffret J, Denizot A, Plan M. The nonrecurrent inferior laryngeal nerve: review of 33 cases, including two on the left side. Surgery. 1988;104(6): 977–84.
Kobayashi M, Yuta A, Okamoto K, Majima Y. Non-recurrent inferior laryngeal nerve with multiple arterial abnormalities. Acta Otolaryngol. 2007;127(3): 332–6.
Toniato A, Mazzarotto R, Piotto A, Bernante P, Pagetta C, Pelizzo MR. Identification of the nonrecurrent laryngeal nerve during thyroid surgery: 20-year experience. World J Surg. 2004;28(7):659–61.
Hong KH, Park HT, Yang YS. Characteristic travelling patterns of non-recurrent laryngeal nerves. J Laryngol Otol. 2014;128(6):534–9.
Katz AD, Nemiroff P. Anastamoses and bifurcations of the recurrent laryngeal nerve—report of 1177 nerves visualized. Am Surg. 1993;59(3):188–91.
Reeve TS, Coupland GA, Johnson DC, Buddee FW. The recurrent and external laryngeal nerves in thyroidectomy. Med J Aust. 1969;1(8):380–2.
Hisham AN, Lukman MR. Recurrent laryngeal nerve in thyroid surgery: a critical appraisal. ANZ J Surg. 2002;72(12):887–9.
Sagayaraj A, Deo RP, Merchant S, Mohiyuddin SM, Nayak AC. Medially placed vagus nerve in relation to common carotid artery: a pointer to a non-recurrent laryngeal nerve. Eur Arch Otorhinolaryngol. 2015;272(10):3027–30.
Toniato A, Merante Boschin I, Pagetta C, Casalide E, Pelizzo M. A “pilot light” of the right non-recurrent laryngeal nerve. Acta Otorhinolaryngol Ital. 2010;30(2):107–9.
Sogutlu G, Olmez A, Firat Y, et al. Non-recurrent inferior laryngeal nerves: report of two cases and review of the literature. ANZ J Surg. 2007;77(7):601–2.
Proye CA, Carnaille BM, Goropoulos A. Nonrecurrent and recurrent inferior laryngeal nerve: a surgical pitfall in cervical exploration. Am J Surg. 1991;162(5):495–6.
Sanders G, Uyeda RY, Karlan MS. Nonrecurrent inferior laryngeal nerves and their association with a recurrent branch. Am J Surg. 1983;146(4):501–3.
Raffaelli M, Iacobone M, Henry JF. The “false” nonrecurrent inferior laryngeal nerve. Surgery. 2000; 128(6):1082–7.
Fellmer PT, Bohner H, Wolf A, Roher HD, Goretzki PE. A left nonrecurrent inferior laryngeal nerve in a patient with right-sided aorta, truncus arteriosus communis, and an aberrant left innominate artery. Thyroid. 2008;18(6):647–9.
Corone P, Vernant P. Anomalies des arcs aortiques. EMC Coeur et Vaisseaux 11040 M 50; 21–28. 1970.
Chandrasekhar SS, Randolph GW, Seidman MD, et al. Clinical practice guideline: improving voice outcomes after thyroid surgery. Otolaryngol Head Neck Surg. 2013;148(6 Suppl):S1–37.
Brauckhoff M, Gimm O, Thanh PN, et al. First experiences in intraoperative neurostimulation of the recurrent laryngeal nerve during thyroid surgery of children and adolescents. J Pediatr Surg. 2002;37(10): 1414–8.
Chiang FY, Lu IC, Tsai CJ, Hsiao PJ, Lee KW, Wu CW. Detecting and identifying nonrecurrent laryngeal nerve with the application of intraoperative neuromonitoring during thyroid and parathyroid operation. Am J Otolaryngol. 2012;33(1):1–5.
Donatini G, Carnaille B, Dionigi G. Increased detection of non-recurrent inferior laryngeal nerve (NRLN) during thyroid surgery using systematic intraoperative neuromonitoring (IONM). World J Surg. 2013;37(1):91–3.
Kamani D, Potenza AS, Cernea CR, Kamani YV, Randolph GW. The nonrecurrent laryngeal nerve: anatomic and electrophysiologic algorithm for reliable identification. Laryngoscope. 2015;125(2):503–8.
Watanabe A, Taniguchi M, Kimura Y, Ito S, Hosokawa M, Sasaki S. Efficient, effective, safe procedure to identify non-recurrent inferior laryngeal nerve during thyroid surgery. Head Neck. 2014. doi:10.1002/hed.23932.
Ardito G, Manni R, Vincenzoni C, Modugno P, Guidi ML. The non-recurrent inferior laryngeal nerve. Surgical experience. Ann Ital Chir. 1998;69(1):21–4.
Defechereux T, Albert V, Alexandre J, Bonnet P, Hamoir E, Meurisse M. The inferior non recurrent laryngeal nerve: a major surgical risk during thyroidectomy. Acta Chir Belg. 2000;100(2):62–7.
Dolezel R, Jarosek J, Hana L, Ryska M. Clinical relevance and surgical anatomy of non-recurrent laryngeal nerve: 7 year experience. Surg Radiol Anat. 2015;37(4):321–5.
Geraci G, Lo Nigro C, Sciuto A, Arone E, Modica G, Sciume C. Non-recurrent laryngeal nerve coexisting with ipsilateral recurrent nerve: personal experience and literature review. G Chir. 2011;32(5):251–4.
Page C, Monet P, Peltier J, Bonnaire B, Strunski V. Non-recurrent laryngeal nerve related to thyroid surgery: report of three cases. J Laryngol Otol. 2008;122(7):757–61.
Stewart GR, Mountain JC, Colcock BP. Non-recurrent laryngeal nerve. Br J Surg. 1972;59(5):379–81.
Tartaglia F, Blasi S, Tromba L, et al. Duplex ultrasound and magnetic resonance imaging of the supra-aortic arches in patients with non recurrent inferior laryngeal nerve: a comparative study. G Chir. 2011;32(5):245–50.
Vallicioni J, Ndiaye M, Poissonnet G, et al. Nonrecurrent inferior laryngeal nerve: review of 13 cases. Ann Otolaryngol Chir Cervicofac. 2003;120(5): 268–70.
Vuillard P, Bouchet A, Gouillat C, Armand D. Non-recurrent inferior laryngeal nerve (15 operative cases). Bull Assoc Anat. 1978;62(179):497–505.
Wijetilaka SE. Non-recurrent laryngeal nerve. Br J Surg. 1978;65(3):179–81.
Yetisir F, Salman AE, Ciftci B, Teber A, Kilic M. Efficacy of ultrasonography in identification of non-recurrent laryngeal nerve. Int J Surg. 2012;10(9): 506–9.
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Lubitz, C.C., Kraus, D.H., Randolph, G.W., Wong, R.J. (2016). The Nonrecurrent Inferior Laryngeal Nerve. In: Randolph, G. (eds) The Recurrent and Superior Laryngeal Nerves. Springer, Cham. https://doi.org/10.1007/978-3-319-27727-1_11
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DOI: https://doi.org/10.1007/978-3-319-27727-1_11
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