Abstract
Nematodes are believed to have originated 1000 million years ago as free living anaerobic benthic organisms. Modern anthelmintic drugs have been in use but the worms have created resistance to most of the broad spectrum anthelmintics such as benzimidazoles, levamisole, avermectins, etc. However, these drugs cause side effects. More recently, plant extracts have been reported as having developed resistance against anthelmintics. A study using earthworms to determine the activity has been developed and explained in a well-defined manner in this chapter.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ajaiyeoba, E. O., Onocha, P. A., & Olarenwaju, O. T. (2001). In vitro anthelmintic properties of Buchholzia coriaceae and Gynandropsis gynandra extracts. Pharmaceutical Biology, 39, 217–220.
Thorn, G. W., Adams, R. D., Braunwald, E., Isselbacher, K. J., & Petersdorf, R. G. (1977). Principles of internal medicine. New York: McGraw Hill Co.
Vigar, Z. (1984). Atlas of medical parasitology (2nd ed.). Singapore: P.G. Publishing House.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Thangaraj, P. (2016). In Vitro Anthelmintic Assay. In: Pharmacological Assays of Plant-Based Natural Products. Progress in Drug Research, vol 71. Springer, Cham. https://doi.org/10.1007/978-3-319-26811-8_12
Download citation
DOI: https://doi.org/10.1007/978-3-319-26811-8_12
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-26810-1
Online ISBN: 978-3-319-26811-8
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)