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Bioinks for Bioprinting

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Bioprinting in Regenerative Medicine

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

Three-dimensional bioprinting has developed as new technology to support regenerative medicine. The major components of bioprinting include computer aided design of constructs, instruments to “print” structures, and the focus of this chapter, bioinks. Bioinks are composed of several components including solutions and gels that provide structure to the printed component, cells and additives that are used to alter the structure of the printed solutions and gels. The most commonly used bioink solutions are derived from natural products including alginate and agarose. Proteins that undergo self assembly are also commonly used and include purified interstitial collagen. A new generation of printable gels are emerging that include materials that undergo solution to gel transition at specific temperatures. Also considered are the chemistries that support the formation of stable gels. These chemistries include chemical cross-linking agents and photoinitiators that can support UV and visible light activated cross linking of materials.

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Authors and Affiliations

  1. Bioficial Organs Program, Cardiovascular Innovation Institute, University of Louisville, 40202, Louisville, KY, USA

    Stuart K. Williams PhD

  2. Chief, Division of Cardiovascular Therapeutics, Cardiovascular Innovation Institute, University of Louisville, 40202, Louisville, KY, USA

    James B. Hoying PhD

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  1. Sprott Centre for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, Canada

    Kursad Turksen

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Williams, S., Hoying, J. (2015). Bioinks for Bioprinting. In: Turksen, K. (eds) Bioprinting in Regenerative Medicine. Stem Cell Biology and Regenerative Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-21386-6_1

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