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Bioactive Glass-Biopolymer Composites for Applications in Tissue Engineering

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Handbook of Bioceramics and Biocomposites

Abstract

Tissue engineering (TE) is a biomedical field in continuous expansion. However, there are still many challenges to be tackled. The further development of TE approaches requires interdisciplinary interaction and collaboration among various research areas with a notable contribution expected from biomaterials science. In the last couple of decades, significant advances in the development of biomaterial-based scaffolds for hard and soft tissue regeneration have been accomplished, including the manufacture of biocomposites that combine natural or synthetic polymers with bioactive glasses or glass-ceramics. These novel biomaterials present the possibility of tailoring a variety of parameters and properties such as degradation kinetics, mechanical properties, and chemical composition according to the aimed application. This chapter presents a concise update of the field of biopolymer–bioactive glass composite scaffold development for TE covering several popular processing techniques for biocomposite fabrication, namely, microsphere processing, solvent casting-particulate leaching method, electrospinning, freeze-drying, and rapid prototyping techniques, which lead to scaffolds exhibiting a variety of 3D morphologies and different pore structures.

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Authors and Affiliations

  1. Institute of Polymer Materials, University of Erlangen-Nuremberg, 91058, Erlangen, Germany

    Yaping Ding, Dirk W. Schubert & Judith A. Roether

  2. Department of Materials Engineering, Federal University of São Carlos, Rodovia Washington Luís, Km 235, s/n - Jardim Guanabara, 13565-905, São Carlos, SP, Brazil

    Marina T. Souza

  3. Institute of Biomaterials, University of Erlangen-Nuremberg, 91058, Erlangen, Germany

    Wei Li & Aldo R. Boccaccini

Authors
  1. Yaping Ding
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  2. Marina T. Souza
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  3. Wei Li
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  4. Dirk W. Schubert
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  5. Aldo R. Boccaccini
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  6. Judith A. Roether
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Correspondence to Judith A. Roether .

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  1. University Politehnica of Bucharest, Bucharest, Romania

    Iulian Vasile Antoniac

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Ding, Y., Souza, M.T., Li, W., Schubert, D.W., Boccaccini, A.R., Roether, J.A. (2016). Bioactive Glass-Biopolymer Composites for Applications in Tissue Engineering. In: Antoniac, I. (eds) Handbook of Bioceramics and Biocomposites. Springer, Cham. https://doi.org/10.1007/978-3-319-12460-5_17

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