DNA Fingerprinting: Approaches and Applications

1. Front Matter

   Pages i-x

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2. Molecular Genetics of Hypervariable DNA

   1. Principles and Recent Advances in Human DNA Fingerprinting

      • A. J. Jeffreys, N. J. Royle, I. Patel, J. A. L. Armour, A. MacLeod, A. Collick et al.

      Pages 1-19

   2. Generation of Variability at VNTR Loci in Human DNA

      • R. Wolff, Y. Nakamura, S. Odelberg, R. Shiang, R. White

      Pages 20-38

   3. Human VNTR Sequences in Porcine HTF-Islands

      • B. Brenig, G. Brem

      Pages 39-49

   4. Oligonucleotide Fingerprinting Using Simple Repeat Motifs: A Convenient, Ubiquitously Applicable Method to Detect Hypervariability for Multiple Purposes

      • J. T. Epplen, H. Ammer, C. Epplen, C. Kammerbauer, R. Mitreiter, L. Roewer et al.

      Pages 50-69

   5. DNA Fingerprinting of the Human Intestinal Parasite Giardia intestinalis with Hypervariable Minisatellite Sequences

      • P. Upcroft

      Pages 70-84

   6. Human Variable Number of Tandem Repeat Probes As a Source of Polymorphic Markers in Experimental Animals

      • B. de Gouyon, C. Julier, P. Avner, M. Georges, M. Lathrop

      Pages 85-94

   7. DNA Fingerprinting: The Utilization of Minisatellite Probes to Detect a Somatic Mutation in the Proteus Syndrome

      • C. E. Schwartz, A. M. Brown, V. M. Der Kaloustian, J. J. McGill, R. A. Saul

      Pages 95-105

   8. Genetic Variability of a Satellite Sequence in the Dipteran Musca domestica

      • A. Blanchetot

      Pages 106-112

3. Population Genetics and Evolutionary Biology

   1. Analysis of Population Genetic Structure by DNA Fingerprinting

      • M. Lynch

      Pages 113-126

   2. Population Genetics of Hypervariable Loci: Analysis of PCR Based VNTR Polymorphism Within a Population

      • R. Chakraborty, M. Fornage, R. Gueguen, E. Boerwinkle

      Pages 127-143

   3. Population Genetic Data Determined For Five Different Single Locus Minisatellite Probes

      • L. Henke, S. Cleef, M. Zakrzewska, J. Henke

      Pages 144-153

   4. Multilocus and Single Locus Minisatellite Analysis in Population Biological Studies

      • T. Burke, O. Hanotte, M. W. Bruford, E. Cairns

      Pages 154-168

   5. Helpers-at-the-nest in European Bee-eaters (Merops apiaster): a Genetic Analysis

      • C. S. Jones, C. M. Lessells, J. R. Krebs

      Pages 169-192

   6. Cloning, Characterization and Evolution of Indian Peafowl Pavo cristatus Minisatellite Loci

      • O. Hanotte, T. Burke, J. A. L. Armour, A. J. Jeffreys

      Pages 193-216

   7. Use of Sex-Linked Minisatellite Fragments to Investigate Genetic Differentiation and Migration of North American Populations of the Peregrine Falcon (Falco peregrinus)

      • J. L. Longmire, R. E. Ambrose, N. C. Brown, T. J. Cade, T. L. Maechtle, W. S. Seegar et al.

      Pages 217-229

4. Economically-important Animals and Plants

   1. Hypervariable DNA Markers and their Applications in the Chicken

      • M. W. Bruford, T. Burke

      Pages 230-242

   2. Cloning of Hypervariable Minisatellite and Simple Sequence Microsatellite Repeats for DNA Fingerprinting of Important Aquacultural Species of Salmonids and Tilapia

      • P. Bentzen, A. S. Harris, J. M. Wright

      Pages 243-262

   3. Genetic Factors Accountable for Line-specific DNA Fingerprint Bands in Quail

      • J. Hillel, O. Gal, T. Schaap, A. Haberfeld, Y. Plotsky, H. Marks et al.

      Pages 263-273

   4. Identification of Markers Associated with Quantitative Trait Loci in Chickens by DNA Fingerprinting

      • U. Kuhnlein, D. Zadworny, J. S. Gavora, R. W. Fairfull

      Pages 274-282

Although DNA fingerprinting is a very young branch of molecular genetics, being barely six years old, its recent impact on science, law and politics has been dramatic. The application of DNA finger­ printing to forensic and legal medicine has guaranteed a high public profile for this technology, and indeed, scarcely a week goes by with­ out the press reporting yet another crime successfully solved by molec­ ular genetics. Less spectacularly, but equally importantly, DNA typing methods are steadily diffusing into an ever wider set of applications and research fields, ranging from medicine through to conservation biology. To date, two DNA fingerprinting workshops have been held in the UK, one in 1988 organised by Terry Burke at the University of Leicester, and the second in 1989 at the University of Nottingham, co-ordinated by David Parkin. In parallel with these workshops, which have provided an important focus for researchers, Bill Amos and Josephine Pemberton in Cambridge have established an informal newsletter "Fingerprint News" which is playing a major role as a forum for DNA fingerprinters. By 1989, it was clear that the field had broadened sufficiently to warrant a full international meeting. As a result, Gaudenz Dolf took on the task of organising the first, of what I hope will be many, International Symposium of DNA Fingerprinting held at Bern during Ist-3rd October 1990. The success of the meeting can be judged from the remarkable attendance, with 270 delegates from no less than 30 countries.

• DNA
• Evolution
• Mutation
• PCR
• calculus
• evolutionary biology
• genetics

• Dept. Zoology, University of Leicester, Leicester, England

  Terry Burke

• Institut für Tierzucht, Universität Bern, Bern, Switzerland

  Gaudenz Dolf

• Dept. Genetics, University of Leicester, Leicester, England

  Alec J. Jeffreys

• UCSF-HSE 1556, San Francisco, USA

  Roger Wolff

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