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Antimicrobial Nanotechnology in Preventing the Transmission of Infectious Disease

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Preclinical Evaluation of Antimicrobial Nanodrugs

Part of the book series: Nanotechnology in the Life Sciences ((NALIS))

Abstract

Infections acquired in the hospital are one of the greatest threats to public health by increasing the morbidity and mortality of affected patients. In this way, it is necessary to implement robust and innovative control measures that prevent the formation of biofilms and the dissemination inside hospital areas. Thus, nanotechnology offers innovative solutions through the design and development of nanosurfaces capable of reducing the transmission, virulence, and infectivity of pathogenic microorganisms within medical care. In this order of ideas, the methods and protocols for evaluating nanomaterials functionalized with bioactive molecules applied to surfaces and medical devices acquire radical importance in order to determine activity and safety. For this reason the objective of this chapter is to make a comprehensive analysis of this interesting approach, in order to develop alternatives for control and prevention of infectious disease with low toxicity and an adequate safety margin, which allows the implementation of hospital environments more biosafety and with greater protection for communities.

There is a difficulty with only one person changing. People call that person a great saint or a great mystic or a great leader, and they say, ‘Well, he’s different from me – I could never do it.’ What’s wrong with most people is that they have this block – they feel they could never make a difference, and therefore, they never face the possibility, because it is too disturbing, too frightening

Space is not empty. It is full, a plenum as opposed to a vacuum, and is the ground for the existence of everything, including ourselves. The universe is not separate from this cosmic sea of energy

Thus, in scientific research, a great deal of our thinking is in terms of theories. The word ‘theory’ derives from the Greek ‘theoria’, which has the same root as ‘theatre’, in a word meaning ‘to view’ or ‘to make a spectacle’. Thus, it might be said that a theory is primarily a form of insight, i.e. a way of looking at the world, and not a form of knowledge of how the world is

― David Bohm (1917–1992)

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Acknowledgments

The author thanks Sebastian Ritoré for his collaboration and invaluable support during the writing of this chapter, as well as the graphics contained in this book.

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  1. Senior Researcher, Research Center of Bioprospecting and Biotechnology for Biodiversity Foundation (BIOLABB), Armenia, Quindio, Colombia

    Juan Bueno

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Bueno, J. (2020). Antimicrobial Nanotechnology in Preventing the Transmission of Infectious Disease. In: Preclinical Evaluation of Antimicrobial Nanodrugs. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-43855-5_6

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