Abstract
Acute immune thrombocytopenia (ITP) is the most common acquired bleeding disorder with peak presentation in the preschool age group. ITP is characterized by sudden onset of mucocutaneous bleeding and platelet count <100,000/mm3 without an alternative etiology. The thrombocytopenia culminates from autoantibody production, increased platelet removal, and, at times, reduced platelet production. Typical management may include careful observation and/or immune modulation to increase platelet survival. As up to 80% of patients will have normalization of platelet counts within 6 months, acute ITP is generally considered a benign childhood disorder.
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Rose, M.J., Jacobson-Kelly, A. (2020). Approach to a Patient with Sudden Onset of Mucocutaneous Bleeding and Thrombocytopenia. In: Dunn, A., Kerlin, B., O'Brien, S., Rose, M., Kumar, R. (eds) Pediatric Bleeding Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-31661-7_13
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DOI: https://doi.org/10.1007/978-3-030-31661-7_13
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