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Physical Activity, Fitness, and Sexual Dysfunction

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Abstract

Erectile dysfunction is a major health problem that affects approximately 15–20% of the general population. Its prevalence is significantly higher (30–80%) in patients with cardiovascular (CV) risk factors or disease. Erectile dysfunction shares common pathophysiological mechanisms with CV disease which include a complex interaction between subclinical inflammation, endothelial dysfunction, atherosclerosis, and arterial structural damage. Roles of exercise and cardiorespiratory fitness (CRF) have been well established as first-line recommendations in the management of hypertension, diabetes, dyslipidemia, obesity, or overt CV disease. In the setting of erectile dysfunction, several observational studies have assessed the impact of exercise on sexual dysfunction, with various studies showing promising results. In addition, randomized trials in various subpopulations with sexual dysfunction suggest significant ameliorating effects of exercise on erectile function. However, these studies are few, and most are not adequately powered to strongly support these benefits. Nevertheless, international guidelines recommend lifestyle interventions – including exercise – as the first step in the management of all patients with sexual dysfunction. Larger well-designed trials are needed to prove the benefits observed in the few available studies.

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Imprialos, K.P., Stavropoulos, K., Doumas, M. (2019). Physical Activity, Fitness, and Sexual Dysfunction. In: Kokkinos, P., Narayan, P. (eds) Cardiorespiratory Fitness in Cardiometabolic Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-04816-7_22

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