Skip to main content

Abstract

Cephalic development involves extremely complex morphogenetic mechanisms built on conserved elements that have undergone enormous evolutionary changes. Transient expressions of phylogenetic origins characterize ontogeny so that the development of the human nose fleetingly reflects different evolutionary stages. In this way, it can be said that development mirrors evolution.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    Experiments in different mammals (cattle, goats, rabbits, mice, rats, hamsters, etc.) have shown that the activity of the alkaloids found in Veratrum californicum were not specific for sheep.

References

  • Cohen M (2002) Malformations of the craniofacial region: evolutionary, embryonic, genetic, and clinical perspectives. Am J Med Genet 115:245–268

    Article  PubMed  Google Scholar 

  • DeMyer W, Zeman W et al (1964) The face predicts the brain: diagnostic significance of median facial anomalies for holoprosencephaly (arhinencephaly). Pediatrics 34(2):256–263

    PubMed  CAS  Google Scholar 

  • Gaffield W, Keeler R (1996) Steroidal alkaloid teratogens: molecular probes for investigation of craniofacial malformations. J Toxicol Toxin Rev 15(4):303–326

    Article  CAS  Google Scholar 

  • Goodman F (2003) Congenital abnormalities of body patterning: embryology revisited. Lancet 362:651–662

    Article  PubMed  Google Scholar 

  • Gould S (ed) (1989) Wonderful life. WW Norton & Company Ltd, New York

    Google Scholar 

  • Nishimura H, Okamoto N (eds) (1976) Sequential atlas of human congenital malformations. University Park Press, Baltimore

    Google Scholar 

  • Roessler E, Muenke M (1998) Holoprosencephaly: a paradigm for the complex genetics of the brain development. J Inherit Metab Dis 21:481–497

    Article  PubMed  CAS  Google Scholar 

  • Shiota K, Yamada S et al (2007) Embryogenesis of holoprosencephaly. Am J Med Genet 143A:3079–3087

    Article  PubMed  Google Scholar 

  • Sperber G (1992) Current concepts in embryonic craniofacial development. Crit Rev Oral Biol Med 4(1):67–72

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag France

About this chapter

Cite this chapter

Jankowski, R. (2013). The Nose in Midface Development. In: The Evo-Devo Origin of the Nose, Anterior Skull Base and Midface. Springer, Paris. https://doi.org/10.1007/978-2-8178-0422-4_13

Download citation

  • DOI: https://doi.org/10.1007/978-2-8178-0422-4_13

  • Published:

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0421-7

  • Online ISBN: 978-2-8178-0422-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics