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Neurologic Complications of Head and Neck Cancer

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Cancer Neurology in Clinical Practice

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Abstract

Head and neck cancer accounts for approx 4–5% of all newly diagnosed cases of cancer in the United States, with estimated numbers of diagnoses and deaths in 2000 were 40,300 and 11,700, respectively (1). Worldwide, more than 600,000 new cases are projected annually (2). More than 90% of head and neck cancer is squamous cell carcinoma in histology, and the majority of tumors are associated with smoking and alcohol use (3). Repeated exposure of the upper aerodigestive tract from the oral cavity to the bronchial trees leads to epithelial damage (condemned mucosa syndrome) and initiation of carcinogenesis (4–6).

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  1. David Schiff MD
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  2. Dong M. Shin MD
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  3. Paul L. Moots MD
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  4. Ronald G. Wiley MD
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Editors and Affiliations

  1. Department of Neurology, University of Virginia Medical Center, Charlottesville, VA, USA

    David Schiff MD

  2. Center for Neuro-Oncology Dana-Farber Cancer Institute; and Department of Neurology, Brigham and Women’s Hospital, Boston, MA, USA

    Patrick Y. Wen MD

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Schiff, D., Shin, D.M., Moots, P.L., Wiley, R.G. (2003). Neurologic Complications of Head and Neck Cancer. In: Schiff, D., Wen, P.Y. (eds) Cancer Neurology in Clinical Practice. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-317-0_30

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