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Hydrogel Printing Based on UV-Induced Projection for Cell-Based Microarray Fabrication

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Cell-Based Microarrays

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1771))

Abstract

A considerable number of studies have focused on fabrication of hydrogel microstructures due to its wide applications in tissue engineering, drug delivery, and extracellular matrix construction. Here, we introduce a hydrogel printing method based on UV-induced projection via a digital micromirror device (DMD). Arbitrary microstructures could be fabricated within few seconds (<3) by modulating UV projection using DMD as digital dynamic masks instead of a physical mask, which also offers a high degree of flexibility and repeatability. Furthermore, the ability of PEGDA film to hinder cell adhesion makes it possible to control area over which cells attach.

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Acknowledgments

This work was partially supported by the National Natural Science Foundation of China (Project Nos. 61302003, 61475183, and 61503258), the NSFC/RGC Joint Research Scheme (Project No. 51461165501), and the CAS FEA International Partnership Program for Creative Research Teams.

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Authors and Affiliations

  1. State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, Liaoning, China

    Wenguang Yang, Haibo Yu, Yuechao Wang & Lianqing Liu

Authors
  1. Wenguang Yang
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  2. Haibo Yu
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  3. Yuechao Wang
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  4. Lianqing Liu
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Corresponding author

Correspondence to Lianqing Liu .

Editor information

Editors and Affiliations

  1. Faculty of Technical Chemistry, Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria

    Peter Ertl

  2. Faculty of Technical Chemistry, Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria

    Mario Rothbauer

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Yang, W., Yu, H., Wang, Y., Liu, L. (2018). Hydrogel Printing Based on UV-Induced Projection for Cell-Based Microarray Fabrication. In: Ertl, P., Rothbauer, M. (eds) Cell-Based Microarrays. Methods in Molecular Biology, vol 1771. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7792-5_8

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  • DOI: https://doi.org/10.1007/978-1-4939-7792-5_8

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7791-8

  • Online ISBN: 978-1-4939-7792-5

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