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Botulinum Toxin Therapy for Prevention of Postsurgical Pain

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Botulinum Toxin Treatment of Pain Disorders

Abstract

Postsurgical pain is a common disorder which results from spasm of muscles or sphincters and peripheral nerves after surgery. Persistent postsurgical pain results in application of polypharmacy and may lead to lengthy hospitalization.

This chapter reviews the data in intraoperative, intramuscular, or intra-sphincteric use of botulinum neurotoxins (BoNTs) for relief of postsurgical pain. As examples, five areas of postsurgical pain are chosen in which blinded or prospective, open-label studies are available. These consist of pain syndromes after mastectomy, hemorrhoidectomy, adductor release surgery in cerebral palsy, hernia repair, and cholecystectomy. The collective results of these reports are encouraging. They not only suggest the efficacy of botulinum neurotoxins (mainly onabotulinumtoxinA) for prevention of postsurgical pain but also suggest that treatment with BoNTs in these syndromes may have predictive value regarding the efficacy of certain surgical procedures which are currently employed to relieve such pains.

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Authors and Affiliations

  1. Botulinum Toxin Treatment Program, Yale School of Medicine, New Haven, CT, USA

    Bahman Jabbari (Professor of Neurology and Director)

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  1. Bahman Jabbari
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Jabbari, B. (2015). Botulinum Toxin Therapy for Prevention of Postsurgical Pain. In: Botulinum Toxin Treatment of Pain Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2501-8_13

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  • DOI: https://doi.org/10.1007/978-1-4939-2501-8_13

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2500-1

  • Online ISBN: 978-1-4939-2501-8

  • eBook Packages: MedicineMedicine (R0)

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