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Formation and Regeneration of Nerve Connections pp 133–147Cite as

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The Conditioned Goldfish Retinal Explant as an Experimental Model of Nerve Regeneration

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Abstract

Some years ago, we developed a simple procedure that permitted us to demonstrate neunte outgrowth from cultured expiants of adult goldfish retina. It has since enjoyed considerable application in our laboratory as well as that of others, principally because it provides a vigorous outgrowth of neurites into an environment in which both the growth medium and the substratum can be manipulated experimentally. We describe here in some detail the experimental system, its properties, and several applications. It is particularly appropriate to review its origin in this volume honoring the many contributions of R.M. Gaze to developmental biology.

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Authors
  1. B. W. Agranoff
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  2. A. M. Heacock
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Editor information

Editors and Affiliations

  1. Department of Ophthalmology, New York Medical College, 10595, Valhalla, NY, USA

    Sansar C. Sharma

  2. The Physiological Laboratory, CB2 3EG, Cambridge, England

    James W. Fawcett

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© 1993 Springer Science+Business Media New York

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Agranoff, B.W., Heacock, A.M. (1993). The Conditioned Goldfish Retinal Explant as an Experimental Model of Nerve Regeneration. In: Sharma, S.C., Fawcett, J.W. (eds) Formation and Regeneration of Nerve Connections. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6707-7_11

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  • DOI: https://doi.org/10.1007/978-1-4899-6707-7_11

  • Publisher Name: Birkhäuser, Boston, MA

  • Print ISBN: 978-1-4899-6709-1

  • Online ISBN: 978-1-4899-6707-7

  • eBook Packages: Springer Book Archive

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