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Overview: Potential Role of Segmental Motor Circuitry in Muscle Fatigue

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Book cover Fatigue

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 384))

Abstract

This chapter reviews several mechanisms that the CNS may use to mitigate muscle fatigue, including intrinsic motoneuron properties and feedback systems. The emphasis is on the effects of sensory inputs on spinal cord interneurons including: Renshaw cells; Ib inhibitory interneurons; interneurons mediating presynaptic inhibition; Ia inhibitory interneurons; and interneuronal networks constituting central pattern generators for locomotion. This exercise brings out how little is known about the operation of these circuits in dealing with muscle fatigue.

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Authors and Affiliations

  1. Departments of Clinical Neurosciences and Medical Physiology, The University of Calgary, Faculty of Medicine, 3330 Hospital Drive N.W., Calgary, Alberta, T2N 4N1, Canada

    U. Windhorst & G. Boorman

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  1. U. Windhorst
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  2. G. Boorman
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Editor information

Editors and Affiliations

  1. Prince of Wales Medical Research Institute, Sydney, New South Wales, Australia

    Simon C. Gandevia

  2. The Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Roger M. Enoka

  3. McMaster University, Hamilton, Ontario, Canada

    Alan J. McComas

  4. The University of Arizona, Tucson, Arizona, USA

    Douglas G. Stuart  & Patricia A. Pierce  & 

  5. University of Miami, Miami, Florida, USA

    Christine K. Thomas

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Windhorst, U., Boorman, G. (1995). Overview: Potential Role of Segmental Motor Circuitry in Muscle Fatigue. In: Gandevia, S.C., Enoka, R.M., McComas, A.J., Stuart, D.G., Thomas, C.K., Pierce, P.A. (eds) Fatigue. Advances in Experimental Medicine and Biology, vol 384. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1016-5_19

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  • DOI: https://doi.org/10.1007/978-1-4899-1016-5_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1018-9

  • Online ISBN: 978-1-4899-1016-5

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