Abstract
In protein biosynthesis, or translation, a sequence of mRNA codons directs the polymerization of amino acids into a polypeptide chain. The process is appropriately called translation, since it involves a transfer of genetic information by means of two different “languages” using nucleotides and amino acids.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Selected Readings
Arnstein, H. R. V., and Cox, R. A., Protein Biosynthesis, IRL Press, Oxford (1992).
Austen, B. M., and Westwood, O. M. R., Protein Targeting and Secretion, IRL Press, Oxford (1991).
Dunn, W. A., Jr., Autophagy and related mechanisms of lysosome-me-diated protein degradation, Trends Cell Biol. 4: 139–143 (1994).
Gesteland, R. F., and Atkins, J. F., Recoding: Dynamic programming of translation, Annu. Rev. Biochem. 65: 741–768 (1996).
Graves, D. J., Martin, B. L., and Wang, J. H., Co-and Posttranslation-al Modification of Proteins: Chemical Principles and Biological Effects, Oxford University Press, New York (1994).
Hartl, F U., Molecular chaperones in cellular protein folding, Nature (London) 381: 571–580 (1996).
Hill, W. E. (ed.), The Ribosome: Structure, Function, and Evolution, American Society for Microbiology, Washington (1990).
Holtzman, E., Intracellular targeting and sorting, BioScience 42: 608–620 (1992).
Jacobson, A., and Peitz, S. W., Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells, Annu. Rev. Biochem. 65: 693–739 (1996).
Kawashima, T., Colot-ninas, C. B., Wulff, M., Cusack, S., and Leberman, R., The stucture of the Escherichia coli EF-Tu.EF-Ts complex at 2.5A resolution, Nature (London) 379: 511–518 (1996).
Lieberman, K. R., and Dahlberg, A. E., Ribosome-catalyzed peptide bond formation, Prog. Nucleic Acid Res. Mol. Biol. 50: 1–23 (1995).
Rapoport, T. A., Jungnickel, B., and Kutay, U., Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes, Annu. Rev. Biochem. 65: 271–303 (1996).
Sandoval, I. V., and Bakke, O., Targeting of membrane proteins to en- dosomes and lysosomes, Trends Cell Biol. 4: 292–297 (1994).
Scheffner, M., Nuber, U., and Huibregtse, J. M., Protein ubiquitination involving an El-E2–E3 enzyme ubiquitin thioester cascade, Nature (London) 373: 81–83 (1995).
Tate, W. P., Poole, E. S., and Mannering, S., Hidden infidelities in the translational stop signal, Prog. Nucleic Acid Res. Mol. Biol. 52: 293–335 (1996).
Varshaysky, A., The N-end rule pathway of protein degradation, Genes to Cells 2: 13–28 (1997).
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer Science+Business Media New York
About this chapter
Cite this chapter
Stenesh, J. (1998). Translation—The Synthesis of Protein. In: Biochemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9427-4_19
Download citation
DOI: https://doi.org/10.1007/978-1-4757-9427-4_19
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9429-8
Online ISBN: 978-1-4757-9427-4
eBook Packages: Springer Book Archive