Abstract
Membrane fusion is an essential event in many important physiological and pathological processes, such as neurotransmitter release, endocrine secretion, certain viral infections, etc. The molecular mechanism of membrane fusion remains still unknown; early studies suggested that amphipathic molecules could be involved1; some recent evidence2,3 supports earlier suggestions of the involvement of osmotic phenomena in membrane fusion; changes in water activity at the cell-water interface have also been invoked4. In our studies, we have examined in particular the possible role of water-soluble amphiphiles (i.e. surfactants), in the fusion process: a whole series of hydro-phyllic and lipophyllic surface active reagents have been tested for fusogenic activity by other authors5.
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Goñi, F.M., Alonso, A. (1988). Surfactant-Induced Liposome Fusion: Molecular Mechanisms and Biotechnological Applications. In: Gaber, B.P., Schnur, J.M., Chapman, D. (eds) Biotechnological Applications of Lipid Microstructures. Advances in Experimental Medicine and Biology, vol 238. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-7908-9_8
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DOI: https://doi.org/10.1007/978-1-4684-7908-9_8
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