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Neuronal Activity in the Ventral Striatum of the Primate

  • Conference paper
The Basal Ganglia II

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 32))

Abstract

Since the paper of Heimer and Wilson (1975), great interest has focussed on the anatomy of the ventral striatum, which includes the nucleus accumbens, the olfactory tubercle (or anterior perforated substance of primates), and the islands of Calleja. They showed that the ventral striatum receives inputs from limbic structures such as the amygdala and hippocampus, and projects to the ventral pallidum. The ventral pallidum may then influence output regions by the subthalamic nucleus / globus pallidus / ventral thalamus / premotor cortex route, or via the mediodorsal nucleus of the thalamus / prefrontal cortex route (Heimer et al, 1982). The ventral striatum may thus be for limbic structures what the neostriatum is for neocortical structures, that is a route for limbic structures to influence output regions. The dopamine pathways are at a critical position in these systems, for the nigro-striatal pathway projects to the neostriatum, and the mesolimbic dopamine pathway projects to the ventral striatum (Ungerstedt, 1971). Indeed, Nauta and Domesick (1978) have provided evidence that the ventral striatum also provides a route for limbic information to influence the neostriatum, via the projections of the ventral striatum to the substantia nigra (A9), and thus via the dopamine pathways to the neostriatum. This pattern of connections of the ventral striatum appears to occur not only in the rat (Heimer and Wilson, 1975; Newman and Winans, 1980a,b), but also in the primate (Hemphill et al, 1981). In addition, it is now clear that the olfactory tubercle is in the anterior perforated substance in the primate (Heimer et al, 1977), and that while a small part of it related to the olfactory tract does receive olfactory projections, a much larger part of it receives a strong projection from the inferior temporal visual cortex (Van Hoesen et al, 1976, 1981), and could thus provide a link from temporal lobe association cortex to output regions.

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Authors and Affiliations

  1. Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, 0X1 3UD, England

    Edmund T. Rolls & Graham V. Williams

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  1. Edmund T. Rolls
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  2. Graham V. Williams
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Editors and Affiliations

  1. Department of Anatomy F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, Maryland, USA

    Malcolm B. Carpenter

  2. Department of Neurology School of Medicine, Louisiana State University, New Orleans, Louisiana, USA

    A. Jayaraman

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© 1987 Plenum Press, New York

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Rolls, E.T., Williams, G.V. (1987). Neuronal Activity in the Ventral Striatum of the Primate. In: Carpenter, M.B., Jayaraman, A. (eds) The Basal Ganglia II. Advances in Behavioral Biology, vol 32. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5347-8_24

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  • DOI: https://doi.org/10.1007/978-1-4684-5347-8_24

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