Abstract
The use of the porphyrin product HPD1 for tumor localization (1,2) and therapy (2–5) has been described. One report on an analysis of HPD appeared in 1980 (6) and other such reports are contained in this book. In order to characterize the events leading to tumor localization by HPD, it will be necessary to delineate active components in the product, the nature of any porphyrin transformations associated with the localization process and loci of binding of localized fluorescent porphyrins within the tumor cell.
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Abbreviations
- HPD:
-
hematoporphyrin derivative [product of alkaline hydrolysis after acetylation]
- HP:
-
hematoporphyrin
- HVD:
-
monohydroxyethyl-monovinyldeuteroporphyrin
- PP:
-
protoporphyrin
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© 1983 Plenum Press, New York
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Kessel, D., Chou, TH. (1983). Porphyrin Localizing Phenomena. In: Kessel, D., Dougherty, T.J. (eds) Porphyrin Photosensitization. Advances in Experimental Medicine and Biology, vol 160. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4406-3_12
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DOI: https://doi.org/10.1007/978-1-4684-4406-3_12
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