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The Hippocampus and Hormonal Cyclicity

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The Hippocampus

Abstract

In recent years, considerable importance has been attributed to the role of the hormonal environment in modulating the activity of the central nervous system (CNS) and, conversely, the role of the CNS in regulating endocrine and associated physiological functions. It has become evident that any final analysis of behavior attempting to deal with CNS alterations induced by lesion, stimulation, drugs, etc., must take into account the resultant effects on endogenous levels of hormones. In addition, not only do normal cyclical alterations in the hormonal environment have widespread effects on the CNS, but these effects vary over time. The endocrine-CNS interaction could be an important factor in the complex behavioral changes observed as a result of interruption of either of these systems. This chapter deals specifically with the relationship of the limbic system, especially the hippocampus and amygdala, to alterations in the hormonal environment, with primary emphasis on cyclical changes in gonadal and adrenal steroids.

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McGowan-Sass, B.K., Timiras, P.S. (1975). The Hippocampus and Hormonal Cyclicity. In: Isaacson, R.L., Pribram, K.H. (eds) The Hippocampus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2976-3_14

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