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Luminescence of Polypeptides and Proteins

  • Chapter
Excited States of Proteins and Nucleic Acids

Abstract

It is frequently advantageous to consider the evolution of ideas and results when surveying a particular area of reseach since the early results often contain the fundamental outlines of a problem which subsequently become obscured by the later accumulation of detailed knowledge. The history of the development of protein fluorescence followed a logical pattern and so is quite suitable to discuss with a linear time scale. Because there are many experimental complications presented to investigators of the luminescence of biological macromolecules, each advance in knowledge was and is intimately associated with technological breakthroughs in measurement rather than with advances in theory. Also, because of considerable inherent difficulties in luminescence measurements, many of the initial observations announced were later shown to be in error. So, with apologies to friends and former colleagues for remembering the errors, it is hoped that a brief account of the development of the field will prove to be of value to those who are tempted to enter this difficult area, which is one so susceptible to serious errors.

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Longworth, J.W. (1971). Luminescence of Polypeptides and Proteins. In: Steiner, R.F., Weinryb, I. (eds) Excited States of Proteins and Nucleic Acids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1878-1_8

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  • DOI: https://doi.org/10.1007/978-1-4684-1878-1_8

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