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Nutrition pp 1–39Cite as

Nutrition and Metabolic Development in Mammals

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Part of the book series: Human Nutrition ((HUNU,volume 1))

Abstract

As discussed here, development means the growth and differentiation of an individual. It is important to stress that all the information necessary for the finished product (the adult) is contained in a single fertilized cell. Why this cell starts dividing and differentiating is still a mystery. Basically, development consists of repression and derepression of certain genes. On the whole, development is a “one-way street.” Under ordinary circumstances, there is no return to younger stages, although this is not an absolute impossibility. Thus, it is possible to take the nucleus from an epithelial gut cell of a tadpole, implant it into a fertilized frog cell from which the nucleus has been removed, and obtain from this new cell a whole new tadpole (Gurdon, 1962). On the other hand, it is not possible to alter fully differentiated organs (e.g., the completed brain of a tadpole) once they are made.

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Authors and Affiliations

  1. Centre for Developmental Medicine, Departments of Pediatrics and Obstetrics and Gynaecology, University of British Columbia, Vancouver, B.C., Canada

    Peter Hahn

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  1. Peter Hahn
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  1. Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, New York, USA

    Myron Winick

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Hahn, P. (1979). Nutrition and Metabolic Development in Mammals. In: Winick, M. (eds) Nutrition. Human Nutrition, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7210-7_1

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