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Effects of Ionizing Radiation

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Book cover Alterations of Chemical Equilibrium in the Nervous System

Abstract

The study of the effects of ionizing radiations on both growing and adult CNS appears as an aspect directly related to the general theme of this Handbook, since it refers to the “radiobiochemical lesion” of the neuroaxis. Such effects can resemble those produced by other noxious agents. Because we deal here with the intrinsic mechanism through which the ionizing radiation affects the nervous tissue, there is a radiobiological review at the beginning of the chapter. Neuroradiobiochemistry, one of the least known and cultivated frontiers of neurochemistry, does not represent more than 1 to 2% of the published papers of specialized journals, congresses, or symposia, in spite of the fact that the CNS is structurally the best system of animal economy and biologically the one most apt to register any energy change of the external medium; it could be supposed that the absorption of radiant energy would be rapidly transformed into physicochemical, biochemical, and functional alterations of the system. In this chapter we shall refer to neuroradiochemical facts of major significance, attempting to explain, as far as possible, the eventual mechanisms which may have bearing on such processes. In the past 8 years numerous books, reviews, and articles have been published on the effect of ionizing radiation on CNS. They contain excellent references to the radioneurobiochemical studies.(1–22)

Most of the experimental work reported by E. Egaña et al. in this chapter has been carried out under a grant from the International Atomic Energy Agency, Vienna. Contracts No. 95, RB/1 and RB/2, and, at present, No. 887, also under a grant from the Comisión de la Investigation Cientifica, Faculty of Medicine, University of Chile, 1967–1970.

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Authors and Affiliations

  1. Laboratory of Neurochemistry-Institute of Experimental Medicine School of Medicine, University of Chile, Santiago, Chile

    Enrique Egaña

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  1. New York State Research Institute for Neurochemistry and Drug Addiction, Ward’s Island, New York, New York, USA

    Abel Lajtha

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© 1971 Plenum Press, New York

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Egaña, E. (1971). Effects of Ionizing Radiation. In: Lajtha, A. (eds) Alterations of Chemical Equilibrium in the Nervous System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7175-9_22

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