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Cytokine Patterns Associated with Chronic Fatigue Syndrome

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Abstract

As suggested by its name, the single main characteristic of chronic fatigue syndrome (CSF) is a severe long-lasting disabling fatigue. Both the etiology and pathophysiology of the disease are obscure. The fatigue may be accompanied by other chronic somatic symptoms of varying frequency and severity, and by flu-like symptoms (e.g. pharyngitis, adenopathy, low-grade fever, myalgia, arthralgia, headache) and neurophsychological manifestations (e.g. difficulty in concentrating, exercise intolerance, mental depression and a distrubance in sleep pattern (Holmes et al., 1988; Komaroff, 1993; McCluskey & Riley, 1992). Clinical examination and routine laboratory investigations generally yield no specific abnormalities.

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Authors and Affiliations

  1. Interdisciplinary Department, Bar Ilan University, Ramat Gan, 52900, Israel

    D. Sredni

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  1. D. Sredni
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  1. Bar Ilan University, Ramat Gan, Israel

    Shlomo Yehuda

  2. Boston University, Boston, Massachusetts, USA

    David I. Mostofsky

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© 1997 Springer Science+Business Media New York

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Sredni, D. (1997). Cytokine Patterns Associated with Chronic Fatigue Syndrome. In: Yehuda, S., Mostofsky, D.I. (eds) Chronic Fatigue Syndrome. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5953-5_7

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  • DOI: https://doi.org/10.1007/978-1-4615-5953-5_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7728-3

  • Online ISBN: 978-1-4615-5953-5

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