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Late effects of cancer therapy

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Diagnostic and Therapeutic Advances in Pediatric Oncology

Part of the book series: Cancer Treatment and Research ((CTAR,volume 92))

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Abstract

Concern about late effects of chemotherapy is a novel problem for the oncologist. As late as the 1960s, survival from childhood cancer was less than 20% overall, with many subsets of patients demonstrating even worse outcome [1]. However, in the last three decades, treatment for malignancy in children has become far more effective. By the late 1980s, 60% to 70% of children with cancer (figure 1) were surviving their illness [2]. Although outcomes were less favorable for certain types of malignancy (figure 2), it is estimated that by the year 2000, one in 900 young adults will be a survivor of childhood cancer [3]. This has created a new area of concern for pediatricians, oncologists, and internists. Dealing with the late effects of therapy, an unheard- of luxury in the 1960s, has now become a dilemma for patients, practitioners, and families of patients and must take a prominent position in the practice of pediatric oncology.

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Authors
  1. Elaine R. Morgan
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  2. Maureen Haugen
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Editors and Affiliations

  1. Robert H. Lurie Cancer Center, Northwestern University Medical School, Chicago, Illinois, USA

    David O. Walterhouse M.D.  & Susan L. Cohn M.D.  & 

  2. Department of Pediatrics, Children’s Memorial Hospital, Chicago, Illinois, USA

    David O. Walterhouse M.D.  & Susan L. Cohn M.D.  & 

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Morgan, E.R., Haugen, M. (1997). Late effects of cancer therapy. In: Walterhouse, D.O., Cohn, S.L. (eds) Diagnostic and Therapeutic Advances in Pediatric Oncology. Cancer Treatment and Research, vol 92. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5767-8_11

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